Protein Alignment Spn55B and SERPINE2

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 113/378 - (29%)
• Similarity: 191/378 - (50%)
• Gaps: 11/378 - (2%)

  Fly     4 FN-LEFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSN 67
            || |.....|:....::|..:......:|:|.||..|.:.:.:...|:.|.|..::|..:.:..|
Human    34 FNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN 98

  Fly    68 FPPEVAQTFQFVLEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQ 132
            ...::.:.....:...:|.:::.|||.::|:...:::..:.:..|:.:..|..::||....:|..
Human    99 GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACD 163

  Fly   133 AINAWVNAKTQGKITELVSADSFSD-NTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVK 196
            :|||||..:|:..|..|:|.|.... .|||||:||::|||.|..:|..|.|::..|...:.:..:
Human   164 SINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQ 228

  Fly   197 INYMNQKAKFNYGFF---EDLGCTALEMPYQDSDLSMFVLLPQE-RTGIYALAEKLKTVNLVDLA 257
            :..:.|.:.|..|..   .||....:|:||....:||.:.||.| .|.:.|:...:.|..:....
Human   229 VPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWM 293

  Fly   258 DKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMF-TDQAEFSNLLESPEGVFVSKVLHKATIE 321
            ..:..:.|.|..|||......:|.|.||.||||.|| :.:|.|:.:....|.:.||.:|.||.||
Human   294 SIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIE 358

  Fly   322 VNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKN--ILFAGAFVK 372
            |:|:||:|:|||..|::.|  :.|..|..|||||:.|.:...  :||.|...|
Human   359 VSEDGTKASAATTAILIAR--SSPPWFIVDRPFLFFIRHNPTGAVLFMGQINK 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	107/360 (30%)
SERPINE2	XP_005246698.1	serpinE2_GDN	33..408	CDD:381039	112/375 (30%)