Protein Alignment Spn55B and SERPINA10

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 110/370 - (29%)
• Similarity: 188/370 - (50%)
• Gaps: 17/370 - (4%)

  Fly    13 ARFTSEL-FQLLSAGGLKE--NVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE--- 71
            |:.||.. |.||....::.  |:|||||.:...:.....|:.|.|..:|.:.||..:..|.:
Human   116 AKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGL 180

  Fly    72 VAQTFQFVLEKY-RNSNL-LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAI 134
            :...|:.:.|.. ||..| |...:..::.:...:|..:.:..|..:.:|...:||.....|.:.:
Human   181 LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLM 245

  Fly   135 NAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINY 199
            |.::|.:|:|||.:|.  |..:..|:|:|::.:.|||.|...|....||.|.|.:.:.:.:|:..
Human   246 NHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPM 308

  Fly   200 MNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDL-ADKLTVE 263
            |....||...|.::..|..|::|||.:...:.||:  |:.|.:...|...|.:||:. ...:...
Human   309 MYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLM--EKMGDHLALEDYLTTDLVETWLRNMKTR 371

  Fly   264 EVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEEGTE 328
            .:.|.|||||:|...|:.|.|:|:||.::|:..|:.|.|..:...:.||:||.:..|||:|.|||
Human   372 NMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTE 436

  Fly   329 AAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKN--ILFAGAFV 371
            |.|  |::......:.|...:.||||.::|:.:.:  :||.|..|
Human   437 AVA--GILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVV 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	107/363 (29%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	110/370 (30%)