Protein Alignment Spn55B and SERPINA5

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 108/368 - (29%)
• Similarity: 194/368 - (52%)
• Gaps: 28/368 - (7%)

  Fly    15 FTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAK--ALHFVSNFPPEVAQTFQ 77
            ||.:|::.|::....:::.|||.||...:|:...|:...|..:|.:  .|:...:...|:.:.||
Human    48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQ 112

  Fly    78 FVLEKY---RNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWVN 139
            .:|::.   |:...|.:.|.|:......|:..:.||:|..|.::....||..:..|.:.||.:|.
Human   113 QLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177

  Fly   140 AKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKA 204
            .:|:|||.:|:.  :...|..::::|.:.||..|...|:.:.|:|..|:|..|..|::..|:::.
Human   178 KQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRED 240

  Fly   205 KFNYGFFEDLGCTALEMPYQDSDLSMFVL-----LPQERTGIYALAEKLKTVNLVDLADKLTVEE 264
            :::|....:|.|..:.:|||.:..::|:|     :.|...|   |:||    .|..........:
Human   241 QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENG---LSEK----TLRKWLKMFKKRQ 298

  Fly   265 VHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEEGTEA 329
            :.:..|||.::.|.:|.:.|..|||:.:||..|:.|. :.:...:.||:::|||.:||:|.||.|
Human   299 LELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSG-ISNHSNIQVSEMVHKAVVEVDESGTRA 362

  Fly   330 AAATGMIM---MTRMMTFPLQFQADRPFL-YVIWNKKNILFAG 368
            |||||.|.   ..|:.:..|.|  :|||| :::.|  ||||.|
Human   363 AAATGTIFTFRSARLNSQRLVF--NRPFLMFIVDN--NILFLG 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	108/368 (29%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	108/368 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010