DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and serpinf1

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001004539.1	Gene:	serpinf1 / 447800	ZFINID:	ZDB-GENE-040912-2	Length:	406	Species:	Danio rerio

Alignment Length:	374	Identity:	97/374 - (25%)
Similarity:	174/374 - (46%)	Gaps:	30/374 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE 71
            :.|...:.|...||:.|::...|.:|..||.||.........|:......:|.:||.:.:....:
Zfish    43 KLAAATSDFGYNLFRQLASRDTKASVFLSPMSISAAFTQLSMGASERAEKQIYRALRYHTLQDSQ 107

  Fly    72 VAQTFQFVLEKYR-NSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAIN 135
            :..|.:.:|...| ::...:.|.::.:....:|:..|.:::::||....:.:.....|  .:.:|
Zfish   108 LHDTLRDLLSSLRASAKGFKSAERILLARKLRLRLEYLNSVEKQYGERPQILAGGARD--LKTVN 170

  Fly   136 AWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYM 200
            .|...:|.||:.::|.: ....||.|:.:.:.:|||.|..:|.:....|.....|:...| |..|
Zfish   171 DWFKQQTGGKVDQVVPS-PLPRNTALLPVGSAYFKGKWITRFGKPNKMETFRRDGQAPAV-IPMM 233

  Fly   201 NQKAKFNY----GFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLV-DLADKL 260
            .|:   ||    |...|||||..::|.:|. :||:..||.|.|....|.|:..|...| ||::.|
Zfish   234 EQE---NYPVKMGIDSDLGCTIAQVPMEDG-VSMYFFLPDEVTQNLTLIEEALTAEFVQDLSNSL 294

  Fly   261 TVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEE 325
            ...:|.:..|..|:.|...|...|..||:::... :.:.:.:...|  |.::.|.||..:|...|
Zfish   295 HTVKVLLTLPVIKLSYKTNLLPSLSDLGLSEWLA-ETDLTKITSQP--VKLNAVHHKVVLETAPE 356

  Fly   326 GTEAA----AATGMIMMTRMMTFPLQFQADRPFLYVIWNKKN--ILFAG 368
            |.|.|    :|||       .:..|.::.|||||:::.::.:  :||.|
Zfish   357 GAEYASTTPSATG-------QSLGLSYRVDRPFLFLVRDEPSGALLFIG 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	96/368 (26%)
serpinf1	NP_001004539.1	SERPIN	30..403	CDD:294093	97/374 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010