DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and serpine2

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_956478.1	Gene:	serpine2 / 393153	ZFINID:	ZDB-GENE-040426-848	Length:	395	Species:	Danio rerio

Alignment Length:	372	Identity:	120/372 - (32%)
Similarity:	204/372 - (54%)	Gaps:	15/372 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GARFTS---ELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPEVA 73
            |||.:.   ::|..:.....:|||:.||..:.:.:.:...|:.|:|..::...|.:..|.|.::.
Zfish    27 GARGSDLGLQVFMQVLQDRAQENVLLSPHGVASVLGMLLPGAHGDTRRQLLNGLKYKKNGPYKML 91

  Fly    74 QTFQFVLEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWV 138
            :.....|....|::::.:||.|:..||..:|..:.||.:|.:..|:.|::::..:||||:||.||
Zfish    92 RKLHKSLTTKSNADIVTIANALFPNEGFSMKEDFLSANRENFLCESHSVDYSDPEAAAQSINDWV 156

  Fly   139 NAKTQGKITELVSADSFSDN-TRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQ 202
            ...|:|:|..:|:||.|... ||||.:|::.|||.|..:|..:.|:...|..|:....|:..|:|
Zfish   157 KNSTKGQIPSVVTADMFDTALTRLVAVNSIFFKGLWKSRFQPQSTKPRSFTAGDGNTYKVPMMSQ 221

  Fly   203 KAKFNYGFF---EDLGCTALEMPYQDSDLSMFVLLP-QERTGIYALAEKLKTVNLVDLADKLTVE 263
            .:.||.|..   :......:|:||..:.:|||:.|| ::.|.:.::...:.|..:......:...
Zfish   222 LSVFNMGQASTPDGQKYIVIELPYHGNSMSMFIALPTEDSTPLSSILPHISTNTIQSWTKLMNPR 286

  Fly   264 EVHVKFPKFKVDYSLELAEKLKQLGITKMF-TDQAEFSNLLESPEGVFVSKVLHKATIEVNEEGT 327
            .:.:..|||.|:..|:|...||.|||..:| .::|:|.:|  |.|.::|||.|.||.|||||:||
Zfish   287 RMRLLMPKFTVEQELDLETPLKALGIKDIFDQNKADFRHL--SSESIYVSKALQKAKIEVNEDGT 349

  Fly   328 EAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKN--ILFAGAFVK 372
            :|:|.|.:|:..|  :.|.....|||||::|.:..:  |||||...|
Zfish   350 KASATTSVILHAR--SSPPWVTVDRPFLFLIRHNSSGTILFAGQINK 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	118/367 (32%)
serpine2	NP_956478.1	PAI-1_nexin-1	26..395	CDD:239006	120/372 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6540
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030