Protein Alignment Spn55B and SERPINA2

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 100/364 - (27%)
• Similarity: 180/364 - (49%)
• Gaps: 20/364 - (5%)

  Fly    18 ELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE--VAQTFQFVL 80
            :|::.|:......||:.:|.|:....|:...|::.:|..||.:.|:......||  :.:.||.||
Human    63 DLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECFQQVL 127

  Fly    81 EKYRNSNL---LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWVNAKT 142
            :.....:.   |...:.|:|.:..:|...:....|:.|||||.||||...:.|.:.||.:|..:|
Human   128 QALSRPDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTEEAKEQINNYVEKRT 192

  Fly   143 QGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAKFN 207
            ..|:.:||.  ....:|.|.|::.:.|.|.|..||..|....:.|.|.::..:::..:|...:|:
Human   193 GRKVVDLVK--HLKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVDDKTIIRVPMINHLGRFD 255

  Fly   208 YGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKLTVEEVHVKFPKF 272
            .....:|....|...|..:..:.|:|...::  ::.|.|||...:|.::.....:..:::.|||.
Human   256 IHRDRELSSWVLAQHYVGNATAFFILPDPKK--MWQLEEKLTYSHLENIQRAFDIRSINLHFPKL 318

  Fly   273 KVDYSLELAEKLKQLGITKMFTDQAEFSNL-LESPEGVFVSKVLHKATIEVNEEGTEAAAATGMI 336
            .:..:.:|...|:.|||||:|:::|:.|.: .|:|  :.:||.:|.|.:.::|:||||..|..:.
Human   319 SISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAP--LKLSKAVHVAVLTIDEKGTEATGAPHLE 381

  Fly   337 MMTRMMTFPLQFQADRPFLYVIWNKKNI----LFAGAFV 371
            .........:.|  :||||.:|  |.:|    ||.|..|
Human   382 EKAWSKYQTVMF--NRPFLVII--KDDITNFPLFIGKVV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	99/361 (27%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	100/364 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010