DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and RGD1562844

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001333297.1	Gene:	RGD1562844 / 306892	RGDID:	1562844	Length:	296	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	95/276 - (34%)
Similarity:	156/276 - (56%)	Gaps:	14/276 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 EVAQTFQFVLEKYRNSN---LLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQ 132
            ::.:.||.:.:|...|.   .||:||.::|.:..::.|.::.:....|:||.|.::||  :||.:
  Rat    15 DIHRGFQLLFKKLNKSERYFSLRMANGIFVDKTCEVLPTFKESCLRFYNSEMEQLSFA--EAAEE 77

  Fly   133 A---INAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQ 194
            :   :|.||:.:|:|||.||:..||....|||||:|||:.|.:|..:|.|..|.|..|.:.:.|.
  Rat    78 SRKHVNTWVSKQTEGKIPELLPDDSVDFQTRLVLVNALYLKATWGRQFDEGSTREMPFKINKNET 142

  Fly   195 VKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADK 259
            ..:..|.|:..|.|.:.:::..:.|.:||:..:|...||||.|...|..:.|:|....|......
  Rat   143 RPVQMMYQEGIFCYKYVKEVPASLLMIPYKGDELCFLVLLPDESVDISKVEEELTFEKLTAWTQP 207

  Fly   260 LTVEEVHVK--FPKFKVDYSLELAEKLKQLGITKMFTD-QAEFSNLLESPE-GVFVSKVLHKATI 320
            .|:...||:  .||||::...:|...|::|||...|.: :|:.|.:  :|| .:.|||.:||:.:
  Rat   208 DTMSYTHVEVFLPKFKLEEDYDLKSLLQRLGIVDAFEETKADLSAM--APERNLCVSKFVHKSVV 270

  Fly   321 EVNEEGTEAAAATGMI 336
            ||||:|||||||...:
  Rat   271 EVNEKGTEAAAAASSV 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	95/276 (34%)
RGD1562844	NP_001333297.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	228	1.000	Domainoid score	I2400
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	229	1.000	Inparanoid score	I3374
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.970