DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn55B and Serpinb3

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001382662.1	Gene:	Serpinb3 / 304688	RGDID:	1549766	Length:	387	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	140/384 - (36%)
Similarity:	216/384 - (56%)	Gaps:	28/384 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF--VSNFPP 70
            ||:...:||.||::.|...  ::|:.:||.||.|.:|:...|::|.|..:|.|||..  .:..|.
  Rat     4 FAKATTQFTLELYRQLRDS--EDNIFYSPLSIMTALAMLQLGAKGNTEKQIEKALQLSETTKKPK 66

  Fly    71 E----------VAQTFQFVLEKYRNSN---LLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESI 122
            |          |.:.|:.::.:...||   .|:..|.:|..:|......:...||:.|.:..||:
  Rat    67 EKSADSHDEENVHEQFRKIMNQLNKSNGAYDLKSPNSIYGAKGFPFLQTFMEDIKKYYQANVESL 131

  Fly   123 NFA-LNDAAAQAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDI 186
            :|| ..:.:.:.||:||..||.|||.:|....|.:.:|.|||:||::|||.|.|||.|:||.||.
  Rat   132 DFAHAAEESQKKINSWVENKTNGKIKDLFPRGSLNSSTILVLVNAVYFKGQWNHKFDEQRTREDK 196

  Fly   187 FWVGEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTV 251
            ||:.:.....:..|.|..:||:.|.||:....:|:||:..:||||:|||.|..|:..|.|||...
  Rat   197 FWLNKNTSKPVQMMRQTNEFNFIFLEDVQAKMVEIPYKGKELSMFILLPMEIDGLKKLEEKLSAD 261

  Fly   252 NLVDLAD--KLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQ-AEFSNLLESPEGVFVSK 313
            .|:....  .:.:.::::..|:|||....:|...|:.:|:...|..| |:||. :.|.:|:.|||
  Rat   262 TLLAWTSPKNMRMTQLNLSLPRFKVQEKYDLPGPLEHMGMVDAFNPQKADFSG-MSSTKGLVVSK 325

  Fly   314 VLHKATIEVNEEGTEAAAATGMIMMTRMMTFP--LQFQADRPFLYVIW--NKKNILFAG 368
            ||||:.:||||||.|||||||  :.||:::.|  .:|..:|||:..|.  |..:|||.|
  Rat   326 VLHKSFLEVNEEGAEAAAATG--VETRILSAPRTTEFTCNRPFIVFIKPNNTNSILFFG 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	138/379 (36%)
Serpinb3	NP_001382662.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	229	1.000	Inparanoid score	I3374
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.880