DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and Serpina3m

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001257911.1	Gene:	Serpina3m / 299276	RGDID:	735068	Length:	419	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	114/363 - (31%)
Similarity:	190/363 - (52%)	Gaps:	18/363 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF--VSNFPPEVAQTFQ 77
            |...|:::|:.....:||||||.||...:|:...|::|.|.:||.:.|.|  ..::..::.|.|.
  Rat    54 FAFSLYKMLALKNPDKNVVFSPLSISAALAIVSLGAKGNTLEEILEVLRFNLTESYETDIHQGFG 118

  Fly    78 FVLEKYRNSN---LLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWVN 139
            .:|::.....   .:...|.|::.:..|:...:|...:..|..||.:.:|.......:.||.:|.
  Rat   119 HLLQRLSQPGDQVKIITGNALFIDKNLQVLAEFQEKTRALYQVEAFTADFQQPRVTEKLINDYVR 183

  Fly   140 AKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMN-QK 203
            .:|||||.||||  ...:.|.:||:|.|.|:|.|...|..:.|.|..|:|.|:..||::.|. ::
  Rat   184 NQTQGKIQELVS--GLKERTSMVLVNYLLFRGKWKVPFDPDYTFESEFYVDEKRSVKVSMMKIEE 246

  Fly   204 AKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKL---TVEEV 265
            ....|...|:|.|:.||:.|..:..::|:|..:.|  :..:...|:...|....|.|   .::|:
  Rat   247 LTTPYFRDEELSCSVLELKYTGNSSALFILPDKGR--MQQVEASLQPETLKKWKDSLRPRKIDEL 309

  Fly   266 HVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEEGTEAA 330
            ::.......|||||  |.|.:|||..:|:.||:.|.:..:.: :.||:|:||..::|||.|||||
  Rat   310 YLPRLSISTDYSLE--EVLPELGIRDVFSQQADLSRITGAKD-LSVSQVVHKVVLDVNETGTEAA 371

  Fly   331 AATGMIMMTRMMTFPLQFQADRPFLYVI--WNKKNILF 366
            ||||..::.|....|:....:||||..:  .:.:.|||
  Rat   372 AATGANLVPRSGRPPMIVWFNRPFLIAVSHTHGQTILF 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	114/363 (31%)
Serpina3m	NP_001257911.1	SERPIN	56..416	CDD:214513	113/361 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010