DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and Serping1

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_954524.1	Gene:	Serping1 / 295703	RGDID:	735225	Length:	504	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	95/363 - (26%)
Similarity:	170/363 - (46%)	Gaps:	40/363 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FTSELFQLLSAGGLKE-NVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPEVAQTFQF 78
            |:.:|:...||....| |:.||||||.:.:.....|:    .|.....|..:.::|.:.|...|
  Rat   154 FSVKLYHAFSATKKAETNMAFSPFSIASLLTQVLLGA----GDSTKSNLEDILSYPKDFACVHQ- 213

  Fly    79 VLEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWVNAKTQ 143
            .|:.:.:..:..| ::::......::..|.:|....|.|....:. ...||..:.||.||...|.
  Rat   214 TLKAFSSKGVTSV-SQIFHSPDLAIRDTYVNASLSLYGSSPRVLG-PDGDANLKLINTWVAENTN 276

  Fly   144 GKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAKFNY 208
            .||.||:  ||...:||||||||::....|...|.:::......:  :...:|:..::.| |:..
  Rat   277 HKINELL--DSLPSDTRLVLLNAVYLSAKWKKTFEQKKMMASFLY--KNSMIKVPMLSSK-KYPL 336

  Fly   209 GFFEDLGCTA----LEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVN---LVDLADKLTV---E 263
            ..|.|....|    |::.:   :||..:::||..|  :.|.:..|.:|   ...:..||.:   :
  Rat   337 ALFNDQTLKAKVGQLQLSH---NLSFVIMVPQSPT--HQLEDMEKALNPTVFKAILKKLELSKFQ 396

  Fly   264 EVHVKFPKFKVDYS---LELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEVNEE 325
            ..:|..|:.||..|   |.:.|||:...    ||.......|.|.|: :.||.:.|:..:|:.|.
  Rat   397 PTYVMMPRIKVKSSQDMLSIMEKLEFFD----FTYDLNLCGLTEDPD-LQVSSMKHETVLELTET 456

  Fly   326 GTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKN 363
            |.|||||:.:.:...::.|.:|    :|||:::|::::
  Rat   457 GVEAAAASTISVARNLLIFEVQ----QPFLFLLWDQRH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	95/363 (26%)
Serping1	NP_954524.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..132
		SERPIN	150..499	CDD:294093	95/363 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010