DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and Serpinf2

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001011892.1	Gene:	Serpinf2 / 287527	RGDID:	1306692	Length:	491	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	107/389 - (27%)
Similarity:	180/389 - (46%)	Gaps:	79/389 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF-VSNFPPEVAQTFQF 78
            ||::||.|::......|:|.||.|:...::....|::.:|.:.:.:.||. :.:..|.:...|..
  Rat    89 FTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGARNQTLENLQRVLHMNMGSCIPHLLSHFCQ 153

  Fly    79 VLEKYRNSNLLRVANKLYVQEGKQLKPAY--QS-------AIKEQYHSEAESINFALNDAAAQAI 134
            .|    |...:|:|.::|:|:|..:|..:  ||       .:|.....|.:.:|          |
  Rat   154 NL----NPGTIRLAARIYLQKGFPIKDDFLEQSEKLFGAKPVKLTGRQEEDLMN----------I 204

  Fly   135 NAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINY 199
            |.||...|:|||.:.:|  ...|||.|:||||:||.|.|..||....|::|.|.:.|:..|.:..
  Rat   205 NKWVKEATEGKIEDFLS--ELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVAM 267

  Fly   200 MN-QKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTV---NLVDLADKL 260
            |: |.....:...|.........|:| :::|..|::|              |.   |:.::...|
  Rat   268 MHAQSYPLRWFLLEQPEIQVAHFPFQ-NNMSFVVIMP--------------TYFGWNVSEVLANL 317

  Fly   261 TVEEVH----------VKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESP-------EG 308
            |.:.::          |:.||..::..|:|...|.:||:..:|          :||       :.
  Rat   318 TWDTLYQPSMREKPTKVRLPKLHLEQHLDLVATLSKLGLQDLF----------QSPDLRGISDQS 372

  Fly   309 VFVSKVLHKATIEVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKNI---LFAGA 369
            :.||.|.|::|:|::|.|.||||||. ..||||..  ..|..:|||::.|. ::.|   ||.|:
  Rat   373 LVVSSVQHQSTMELSEAGVEAAAATS-TAMTRMSL--SSFFLNRPFIFFIM-EETIGIPLFVGS 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	107/389 (28%)
Serpinf2	NP_001011892.1	alpha2AP	82..433	CDD:239008	107/389 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010