Protein Alignment Spn55B and Serpinb1b

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 370
• Identity: 133/370 - (35%)
• Similarity: 214/370 - (57%)
• Gaps: 19/370 - (5%)

  Fly    15 FTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPEVAQTFQFV 79
            ||.|||..|.......|:.||||||.:.:|:.|.|::|.||.:::|.|||.|  ..::...||.:
Mouse    11 FTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTLHFDS--VEDIHSCFQSL 73

  Fly    80 ---LEKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFA-LNDAAAQAINAWVNA 140
               :.|...|:.|::||:||.::.....|.:.::.::.|.::..:::|. .::.|.:.||.||..
Mouse    74 TAEVSKLGASHTLKLANRLYGEKTYNFLPEFLASTQKMYSADLAAVDFQHASEDARKEINQWVKG 138

  Fly   141 KTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAK 205
            :|:|||.||::.......|:|||:||::|||.|..:|....|....|.:.:::...:..|.||.|
Mouse   139 QTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKTVKMMYQKKK 203

  Fly   206 FNYGFFEDLGCTALEMPYQDSDLSMFVLLPQ----ERTGIYALAEKLKTVNLVDLA--DKLTVEE 264
            |.:|:..||.|..||||||..:|||.:|||:    |.||:..:.|:|....|.:..  :.|...:
Mouse   204 FPFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQLTLGKLHEWTKHENLRNID 268

  Fly   265 VHVKFPKFKVDYSLELAEKLKQLGITKMFTD-QAEFSNLLESPEGVFVSKVLHKATIEVNEEGTE 328
            ||||.|:||::.|..|...|..||:..:|:. :|:.|.:..|.: :||||::||:.::|||:|||
Mouse   269 VHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGMSGSRD-LFVSKIVHKSFVDVNEQGTE 332

  Fly   329 AAAATG---MIMMTRMMTFPLQFQADRPFLYVIWNK--KNILFAG 368
            ||||||   .::..:|.|....|..|.|||:.|.:.  .|::|.|
Mouse   333 AAAATGGIIQVLCEKMPTPQEVFTVDHPFLFFIRHNPTANMIFFG 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	132/368 (36%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	133/370 (36%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		9/26 (35%)