Protein Alignment Spn55B and SERPINA11

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 116/379 - (30%)
• Similarity: 197/379 - (51%)
• Gaps: 40/379 - (10%)

  Fly    15 FTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE--VAQTFQ 77
            |...|::.|:|.. ..|:.|||.||.|.:||...|:|..|:..|.:.|.|.....||  :.|.|:
Human    57 FALRLYKELAADA-PGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR 120

  Fly    78 FVLEKYR--NSNL-LRVANKLYVQEGKQLKPA--YQSAIKEQYHSEAESINFALNDAAAQAINAW 137
            .:|....  :..| |:|.|.|::.  |:|||.  |..:|||.|.:.|.|.||..:....:.||.:
Human   121 SLLHTLALPSPKLELKVGNSLFLD--KRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDY 183

  Fly   138 VNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTE-EDIFWVGEEEQVKINYMN 201
            :..:|.|::.:.:  ..||.:|.:||.|.:.||..|.|.||..:|: ::.|:|.|...:::..|:
Human   184 LRRQTYGQVVDCL--PEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMH 246

  Fly   202 QKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLL-PQERTGIYALAE--------KLKTVNLVDLA 257
            ||....:.:.:||.||.|::.|:.:.|::.||. |.:...:.|..:        :|...:|:||
Human   247 QKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLLDL- 310

  Fly   258 DKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEV 322
                    |:  |:|.:..:..|.:.|.|:|:|.:...:|:||.:....... :|||.|||.:::
Human   311 --------HL--PRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKT-ISKVSHKAMVDM 364

  Fly   323 NEEGTEAAAATGMIMM---TRMMTFPLQFQADRPFLYVIW--NKKNILFAGAFV 371
            :|:||||.||:|::..   ...|:.| ....:||||.::|  ..:::||.|..|
Human   365 SEKGTEAGAASGLLSQPPSLNTMSDP-HAHFNRPFLLLLWEVTTQSLLFLGKVV 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	115/376 (31%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	115/376 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010