DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn55B and Serpinb8

DIOPT Version :9

Sequence 1:NP_524953.1 Gene:Spn55B / 49803 FlyBaseID:FBgn0028983 Length:374 Species:Drosophila melanogaster
Sequence 2:NP_035589.1 Gene:Serpinb8 / 20725 MGIID:894657 Length:374 Species:Mus musculus


Alignment Length:374 Identity:126/374 - (33%)
Similarity:209/374 - (55%) Gaps:15/374 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE 71
            :.:.....|...|.::||......|:.|.|.|:.:.:|:.:.|::|.||.::::.|....|  .:
Mouse     3 DLSEANGSFAISLLKILSEKDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSEVLGLSGN--GD 65

  Fly    72 VAQTFQFVLEKYRNSN---LLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALN-DAAAQ 132
            |.|:||.:|.:...::   ||:.|.:|:.:|.......::.:..:.|.:..|.::||.: :...:
Mouse    66 VHQSFQTLLAEINKTDTQYLLKSACRLFGEESCDFLSTFKESCHKFYQAGLEELSFAKDTEGCRK 130

  Fly   133 AINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKI 197
            .||.||:.||:|||:|::|..:....|:|||:||::|||.|..:|..:.|....|...:|::. :
Mouse   131 HINDWVSEKTEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTNQEKKT-V 194

  Fly   198 NYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDL---ADK 259
            ..|.:.|||..|..:::....|.:||.:.:|||.:|||.|.|.: |:.||..|...:..   .:.
Mouse   195 QMMFKHAKFKMGHVDEVNMQVLALPYAEEELSMVILLPDESTDL-AVVEKALTYEKLRAWTNPET 258

  Fly   260 LTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTD-QAEFSNLLESPEGVFVSKVLHKATIEVN 323
            ||..:|.|..|:.|::.|.:|...|:.||:|..|.: :|:||. :.:.:.|.||||.||..:|||
Mouse   259 LTESQVQVFLPRLKLEESYDLETVLQNLGMTDAFEETRADFSG-MTTKKNVPVSKVAHKCFVEVN 322

  Fly   324 EEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKK--NILFAGAF 370
            ||||||||||.:|...|......:|.||.|||:.||:.|  :|||.|.|
Mouse   323 EEGTEAAAATAVIRNARCCRTEPRFCADHPFLFFIWHHKTSSILFCGRF 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn55BNP_524953.1 SERPIN 13..370 CDD:238101 125/366 (34%)
Serpinb8NP_035589.1 SERPIN 4..374 CDD:294093 126/373 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 1 1.000 - - otm44262
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.930

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