Protein Alignment Spn55B and Serpina1b

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_033270.3
• Gene: Serpina1b / 20701
• MGIID: 891970
• Length: 413
• Species: Mus musculus
• Alignment Length: 376
• Identity: 112/376 - (29%)
• Similarity: 177/376 - (47%)
• Gaps: 21/376 - (5%)

  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF--VSNFP 69
            |.|.....|...|::.|.......|:.|||.||.|..|:...||:|:|..:|.:.|.|  .....
Mouse    43 EIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSE 107

  Fly    70 PEVAQTFQFVLEKYR--NSNL-LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAA 131
            .::.::||.:|:...  :|.| |...|.|:|....:|...:....|..|.:|..|:|||.::.|.
Mouse   108 ADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAK 172

  Fly   132 QAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVK 196
            :.||.:|...|||||.|.|.  ....:|...|.|.:.|||.|...|..|.|||..|.|.:...||
Mouse   173 KVINDFVEKGTQGKIVEAVK--ELDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDKSTTVK 235

  Fly   197 INYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKLT 261
            :..|......:......|....|.|.|..:..::| |||::.    .:....:|:| .:|..|:.
Mouse   236 VPMMMLSGMLDVHHCSILSSWVLLMDYAGNASAVF-LLPEDG----KMQHLEQTLN-KELISKIL 294

  Fly   262 VEE----VHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEV 322
            :..    |.:..|:..:.....|...:..||||::|.:.|:.|.:.|....:.:||.:|||.:.:
Mouse   295 LNRRRRLVQIHIPRLSISGDYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTI 359

  Fly   323 NEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNK--KNILFAGAFV 371
            :|.||||||||  :.....|:.|...:.|.|||::|:.:  ::.:|.|..|
Mouse   360 DETGTEAAAAT--VFEAVPMSMPPILRFDHPFLFIIFEEHTQSPIFVGKVV 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	108/363 (30%)
Serpina1b	NP_033270.3	serpinA1_A1AT	44..412	CDD:381012	111/375 (30%)
		RCL	368..387		5/20 (25%)