Protein Alignment Spn55B and Serpina1a

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 379
• Identity: 115/379 - (30%)
• Similarity: 182/379 - (48%)
• Gaps: 27/379 - (7%)

  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHF--VSNFP 69
            |.|.....|...|::.|.......|:.|||.||.|..|:...||:|:|..:|.:.|.|  .....
Mouse    66 EIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSE 130

  Fly    70 PEVAQTFQFVLEKYR--NSNL-LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAA 131
            .::.::||.:|:...  :|.| |...|.|:|....:|...:....|..|.:|..|:|||.::.|.
Mouse   131 ADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAK 195

  Fly   132 QAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVK 196
            :.||.:|...|||||.|.|.  ....:|...|.|.:.|||.|...|..|.|||..|.|.|...||
Mouse   196 KVINDFVEKGTQGKIAEAVK--KLDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVK 258

  Fly   197 INYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQ-------ERTGIYALAEKLKTVNLV 254
            :..|......:......|....|.|.|..:..::| |||.       |:|    |:::|.:..|:
Mouse   259 VPMMTLSGMLHVHHCSTLSSWVLLMDYAGNATAVF-LLPDDGKMQHLEQT----LSKELISKFLL 318

  Fly   255 DLADKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKAT 319
            :...:|.  ::|  ||:..:.....|...:..||||::|.:.|:.|.:.|....:.:|:.:|||.
Mouse   319 NRRRRLA--QIH--FPRLSISGEYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAV 379

  Fly   320 IEVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNK--KNILFAGAFV 371
            :.::|.||||||.|.:.|:.  |:.|...:.|.|||::|:.:  ::.:|.|..|
Mouse   380 LTIDETGTEAAAVTVLQMVP--MSMPPILRFDHPFLFIIFEEHTQSPIFLGKVV 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	111/366 (30%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	114/378 (30%)