Protein Alignment Spn55B and SERPINA12

DIOPT Version :9

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001291390.1
• Gene: SERPINA12 / 145264
• HGNCID: 18359
• Length: 414
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 104/378 - (27%)
• Similarity: 190/378 - (50%)
• Gaps: 28/378 - (7%)

  Fly     7 EFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPE 71
            |.||.......:|.:.|:......|:..||.||.|..::...|:|..|.|||.:..:|......:
Human    47 ELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKD 111

  Fly    72 VAQTFQFVLEK--YRNSNL-LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQA 133
            :.:.|.:::.:  .:..:| |.:.|.|::.:..|.:..:....|..|.:|....||...:.|.:.
Human   112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQ 176

  Fly   134 INAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKIN 198
            ||.:::.||.|||..|:  ::....|.::|.|.:.|:..|.|:|....|:|:.|::.:...||:.
Human   177 INDFISQKTHGKINNLI--ENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVP 239

  Fly   199 YMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVN---LVDLADK- 259
            .|.:...:..|:.:.|.||.||:|||.:..::|: ||.|        .|||.:.   .||...:
Human   240 MMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFI-LPDE--------GKLKHLEKGLQVDTFSRW 295

  Fly   260 ---LTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESP-EGVFVSKVLHKATI 320
               |:...|.|..|:..:..:.:|.:.|..:|::|:|.:..:.:.:  :| ..:.|.:.:|||.:
Human   296 KTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKI--APHRSLKVGEAVHKAEL 358

  Fly   321 EVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKK--NILFAGAFV 371
            :::|.|||.||.||  ..|..|..||..:.|:|:|.:|:::|  ::||.|..|
Human   359 KMDERGTEGAAGTG--AQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIV 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	100/369 (27%)
SERPINA12	NP_001291390.1	serpinA12_vaspin	40..411	CDD:381026	104/378 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010