Protein Alignment Spn55B and Serpinh1

DIOPT Version :10

• Sequence 1: NP_524953.1
• Gene: Spn55B / 49803
• FlyBaseID: FBgn0028983
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_033955.2
• Gene: Serpinh1 / 12406
• MGIID: 88283
• Length: 417
• Species: Mus musculus
• Alignment Length: 369
• Identity: 91/369 - (24%)
• Similarity: 160/369 - (43%)
• Gaps: 17/369 - (4%)

  Fly    12 GARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPEVAQT- 75
            |..|:  |:|.::.....||::.||..:.:.:.|...|.:..||.: |||:........|...|
Mouse    48 GLAFS--LYQAMAKDQAVENILLSPLVVASSLGLVSLGGKATTASQ-AKAVLSAEKLRDEEVHTG 109

  Fly    76 FQFVLEKYRNSNLLRV----ANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINA 136
            ...:|....||....|    .::||..........:..:.|:.|:.|...|||....:|.|:||.
Mouse   110 LGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINE 174

  Fly   137 WVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMN 201
            |.:..|.||:.|:......:|..  :|:||:.||..|..||..:..:...|.|.....|.:..|:
Mouse   175 WASQTTDGKLPEVTKDVERTDGA--LLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMH 237

  Fly   202 QKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLADKLTVEEVH 266
            :...:||...|......:|||......|:.:|:|.....:..|.:.|....|.....|:..:.|.
Mouse   238 RTGLYNYYDDEKEKLQMVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKAWMGKMQKKAVA 302

  Fly   267 VKFPKFKVDYSLELAEKLKQLGITKMF-TDQAEFSNLLESPEGVFVSKVLHKATIEVNEEGTEAA 330
            :..||..|:.:.:|.:.|..||:|:.. .::|:.|. :...:.::::.|.|....|.:.||....
Mouse   303 ISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSR-MSGKKDLYLASVFHATAFEWDTEGNPFD 366

  Fly   331 AATGMIMMTRMMTFPLQFQADRPFLYVIWNKK--NILFAGAFVK 372
            ..   |.....:..|..|.||.||::::.:.:  ::||.|..|:
Mouse   367 QD---IYGREELRSPKLFYADHPFIFLVRDNQSGSLLFIGRLVR 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	serpin42Da-like	15..368	CDD:381065	88/360 (24%)
Serpinh1	NP_033955.2	serpinH1_CBP1	35..416	CDD:381003	91/369 (25%)
		Prevents secretion from ER. /evidence=ECO:0000305	414..417