DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn55B and serpina10b

DIOPT Version :9

Sequence 1:	NP_524953.1	Gene:	Spn55B / 49803	FlyBaseID:	FBgn0028983	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_009291625.1	Gene:	serpina10b / 100003661	ZFINID:	ZDB-GENE-100716-5	Length:	395	Species:	Danio rerio

Alignment Length:	376	Identity:	108/376 - (28%)
Similarity:	186/376 - (49%)	Gaps:	29/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NLEFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFV---- 65
            |.:||....|..|.|..        .||||||.|:.||.:.....:||.|..||.|.|:..
Zfish    35 NTDFAINLYRKISSLHD--------RNVVFSPLSVSTCFSALLLAAQGSTRTEILKGLNLEALDG 91

  Fly    66 --SNFPPEVAQTFQFVLEKYRNSNL-LRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALN 127
              |...||:.|      :.::|.:| :.....|::.:...|:..:...|:..:::|...::|:..
Zfish    92 GDSRRVPELFQ------QLHQNISLQMEQGTALFLDQHFHLQTNFSQQIQRFFNAEVLRVDFSKP 150

  Fly   128 DAAAQAINAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHKFSEERTEEDIFWVGEE 192
            ......||.:|:.||..|:.|::  :|....|:::|||.:.:||.|...|:...||:..|:|.:.
Zfish   151 AVCRSLINEFVSRKTGRKVLEML--ESVEPLTQMLLLNTIFYKGDWERPFNPNNTEKSRFYVDKY 213

  Fly   193 EQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTGIYALAEKLKTVNLVDLA 257
            ..|::..|..:.||:.....||....|.:||: ...||.:|||.......|:.:::....|....
Zfish   214 NIVQVPMMMLEEKFSVVEDRDLRARVLRLPYR-GGASMLILLPSADADYTAIEDEISAERLHGWI 277

  Fly   258 DKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATIEV 322
            ..:...::.|..|:|::|.|..:.|.|.||||:.:|.|.|:.:.|..... :.||:|||||.|||
Zfish   278 KNMRRMKMEVHLPRFRMDQSYHMHELLPQLGISSVFQDSADLTGLSRDAH-LKVSQVLHKAVIEV 341

  Fly   323 NEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKK--NILFAGAFV 371
            .|:||.||::|.:.:..  .:.|..|..:|||.:.:::::  ::||.|..:
Zfish   342 YEQGTSAASSTSVGITA--YSLPDTFIINRPFFFFLYHEETASLLFMGRVI 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn55B	NP_524953.1	SERPIN	13..370	CDD:238101	105/365 (29%)
serpina10b	XP_009291625.1	Serpin	35..392	CDD:278507	108/376 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910