DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD6 and PPT1

DIOPT Version :9

Sequence 1:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	361	Identity:	119/361 - (32%)
Similarity:	186/361 - (51%)	Gaps:	51/361 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LSNSEANAD---YRLPGALNLNDLLNKLMSFRRSKMQRLP-----------------LLESEVNL 59
            ||:.:||||   |..| .|....|.:...:|:.:|::.:.                 |.:..|..
Yeast   153 LSSFDANADLANYEGP-KLEFEQLYDDKNAFKGAKIKNMSQEFISKMVNDLFLKGKYLPKKYVAA 216

  Fly    60 LCTLARELFLDEPMLL---NVPAP---IRVVGDIHGQFYDLLKILDQCG-YPPQTRYLFLGDYVD 117
            :.:.|..||..||.::   |...|   |.|.||.||||||:|.:..:.| ..|:..|||.||:||
Yeast   217 IISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVD 281

  Fly   118 RGKNSVETITLLLALRVKFPKHIYLLRGNHESQSVNRVYGFFDECKRRYTVKLWKTFVDCYNCMP 182
            ||..|.|...|...|::..|.:.:|.||||||.::|::|||.||||.:|:.:::..|...:..:|
Yeast   282 RGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFAQSFESLP 346

  Fly   183 VAAIISHRIFCCHGGL----SPQLKELSNIESIARPTEVPETGLLCDLLWSDPDRYGFGWTSSDR 243
            :|.:|::.....||||    |..|.:..||:..|:|   |..|...:|||:||.... |...|.|
Yeast   347 LATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQP---PRDGAFMELLWADPQEAN-GMGPSQR 407

  Fly   244 GVSYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNYCGLYDNAGASMGV- 307
            |:.:.:|.|:.::||:.|....:.|:|::...|.:|..|.:|:|||||||||....|.|..:.|
Yeast   408 GLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVIHVV 472

  Fly   308 ------------DKDLVI-SFD-IQRGDIRRIVVRN 329
                        |::|:| :|: ::..||:.:...|
Yeast   473 PGHGILQAGRNDDQNLIIETFEAVEHPDIKPMAYSN 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	104/308 (34%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	102/285 (36%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	112/347 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810