DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpD6 and Ppp6c

DIOPT Version :9

Sequence 1:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_077171.1	Gene:	Ppp6c / 67857	MGIID:	1915107	Length:	305	Species:	Mus musculus

Alignment Length:	300	Identity:	130/300 - (43%)
Similarity:	183/300 - (61%)	Gaps:	10/300 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LNKLMSFRRSKMQRLPLLESEVNLLCTLARELFLDEPMLLNVPAPIRVVGDIHGQFYDLLKILDQ 100
            |:|.:...| :.:.||  |:::..||....:|.|:|..:..|..|:.|.||||||||||.::...
Mouse     6 LDKYVEIAR-QCKYLP--ENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRT 67

  Fly   101 CGYPPQTRYLFLGDYVDRGKNSVETITLLLALRVKFPKHIYLLRGNHESQSVNRVYGFFDECKRR 165
            .|..|.|.|:|:||:||||..|:||.|.||||:.|:|..|.||||||||:.:.:||||:|||:.:
Mouse    68 GGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTK 132

  Fly   166 Y-TVKLWKTFVDCYNCMPVAAIISHRIFCCHGGLSPQLKELSNIESIARPTEVPETGLLCDLLWS 229
            | ....|:.....::.:.|||:|..:|.|.||||||.:|.|..|.:|.|..|:|..|..|||:||
Mouse   133 YGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWS 197

  Fly   230 DPDRYGFGWTSSDRGVSYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNY 294
            ||:... .|..|.||..:|:|..|..:|:..|:..|:|||||:|.:||:|....:||||:|||||
Mouse   198 DPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNY 261

  Fly   295 CGLYDNAGASMGVDKDLVISFDIQRGDIRRIVVRNESVSP 334
            |....|. ||:.|.||:    :.:...:.|.|..:|.|.|
Mouse   262 CYRCGNI-ASIMVFKDV----NTREPKLFRAVPDSERVIP 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	121/266 (45%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	120/261 (46%)
Ppp6c	NP_077171.1	MPP_PP2A_PP4_PP6	5..289	CDD:277360	126/291 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820