Protein Alignment PpD6 and PPP4C

DIOPT Version :10

• Sequence 1: NP_524947.1
• Gene: PpD6 / 49780
• FlyBaseID: FBgn0005779
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_002711.1
• Gene: PPP4C / 5531
• HGNCID: 9319
• Length: 307
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 138/310 - (44%)
• Similarity: 199/310 - (64%)
• Gaps: 15/310 - (4%)

  Fly    32 LNDLLNKLMSFRRSKMQRLPLLESEVNLLCTLARELFLDEPMLLNVPAPIRVVGDIHGQFYDLLK 96
            ::||..::...||.::    :.||||..||..|||:.::|..:..|.:|:.|.||||||||||.:
Human     4 ISDLDRQIEQLRRCEL----IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKE 64

  Fly    97 ILDQCGYPPQTRYLFLGDYVDRGKNSVETITLLLALRVKFPKHIYLLRGNHESQSVNRVYGFFDE 161
            :....|..|:|.|||:||:||||..||||..|||||:|::|..|.|:||||||:.:.:||||:||
Human    65 LFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDE 129

  Fly   162 CKRRY-TVKLWKTFVDCYNCMPVAAIISHRIFCCHGGLSPQLKELSNIESIARPTEVPETGLLCD 225
            |.|:| :|.:|:...:.::.:.::|||..:|||.||||||.::.|..|.:|.|..|||..|.:||
Human   130 CLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCD 194

  Fly   226 LLWSDPDRYGFGWTSSDRGVSYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFS 290
            ||||||:. ..||..|.||..||:|.||:.:|...||.|::|||||:|.:||::.....::||:|
Human   195 LLWSDPED-TTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258

  Fly   291 APNYCGLYDNAGASMGVD----KDLVISFDIQRGDIRRIVVRNESVSPIS 336
            |||||....|..|.:.:|    ||.:| |:....:.|.|    .|..|::
Human   259 APNYCYRCGNVAAILELDEHLQKDFII-FEAAPQETRGI----PSKKPVA 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:472684	130/270 (48%)
PPP4C	NP_002711.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	134/289 (46%)