Protein Alignment PpD6 and PPP2CA

DIOPT Version :10

• Sequence 1: NP_524947.1
• Gene: PpD6 / 49780
• FlyBaseID: FBgn0005779
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_002706.1
• Gene: PPP2CA / 5515
• HGNCID: 9299
• Length: 309
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 129/265 - (48%)
• Similarity: 174/265 - (65%)
• Gaps: 2/265 - (0%)

  Fly    52 LLESEVNLLCTLARELFLDEPMLLNVPAPIRVVGDIHGQFYDLLKILDQCGYPPQTRYLFLGDYV 116
            |.||:|..||..|:|:...|..:..|..|:.|.||:||||:||:::....|..|.|.|||:||||
Human    23 LSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYV 87

  Fly   117 DRGKNSVETITLLLALRVKFPKHIYLLRGNHESQSVNRVYGFFDECKRRY-TVKLWKTFVDCYNC 180
            |||..||||:|||:||:|::.:.|.:|||||||:.:.:||||:|||.|:| ...:||.|.|.::.
Human    88 DRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDY 152

  Fly   181 MPVAAIISHRIFCCHGGLSPQLKELSNIESIARPTEVPETGLLCDLLWSDPDRYGFGWTSSDRGV 245
            :|:.|::..:|||.||||||.:..|.:|.::.|..|||..|.:|||||||||..| ||..|.||.
Human   153 LPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRG-GWGISPRGA 216

  Fly   246 SYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNYCGLYDNAGASMGVDKD 310
            .|.:|:|:.|.|...|...||.||||:|.:||.:...|.:||:|||||||....|..|.|.:|..
Human   217 GYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT 281

  Fly   311 LVISF 315
            |..||
Human   282 LKYSF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:472684	129/265 (49%)
PPP2CA	NP_002706.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	129/265 (49%)