DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpD6 and Ppef1

DIOPT Version :9

Sequence 1:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_038955765.1	Gene:	Ppef1 / 317498	RGDID:	1562772	Length:	664	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	102/334 - (30%)
Similarity:	158/334 - (47%)	Gaps:	65/334 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GALNLNDLLNKLMSFRRSKMQRLPLLESEVNLLC-------TL-----------ARELFLDEPML 74
            |.:::.|      |:...::| .||..:::|||.       ||           ||::....|..
  Rat   124 GLIDVPD------SYDGPRLQ-FPLTFTDINLLLQAFKQQQTLHAHYVLEVLFEARKILKQMPNF 181

  Fly    75 LNV---PA-PIRVVGDIHGQFYDLLKILDQCGYPPQTR-YLFLGDYVDRGKNSVETITLLLALRV 134
            ..:   || .|.:.||:||:..||:.|..:.|.|.:.. |:|.||:||||.||:|.:.:||...:
  Rat   182 TRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSEKNPYVFNGDFVDRGNNSMEILMILLVSFL 246

  Fly   135 KFPKHIYLLRGNHESQSVNRVYGFFDECKRRYTV---KLWKTFVDCYNCMPVAAIISHRIFCCHG 196
            .:|..::|.|||||...:|..|||..|..::|.:   |:.:...:.|..:|:..||.:.|...||
  Rat   247 VYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGKKILQVLEELYTWLPIGTIIDNEILVIHG 311

  Fly   197 GLSPQ-----LKEL--SNIESI-----------------ARPTEVP--------ETGLLCDLLWS 229
            |:|..     |::|  :.::|:                 |.|:|..        |...:.|||||
  Rat   312 GISESTDLNILQQLQRNKMKSVLMPPMSTNQECNIKKNKAGPSEQSASEQLTKLEWEQIIDLLWS 376

  Fly   230 DPDRYGFGWTSSDRGVSYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNY 294
            ||......:.::.||....:|.||..|.|.||...:|.|:|:...||||.....:::|||||.||
  Rat   377 DPRGKKGCYPNTSRGGGCYFGPDVTSKVLNKNQLKMVIRSHECKPDGYEICHDGKVITVFSASNY 441

  Fly   295 CGLYDNAGA 303
            .....|.||
  Rat   442 YEEGSNRGA 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	98/311 (32%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	96/308 (31%)
Ppef1	XP_038955765.1	IQ	40..>57	CDD:197470
		MPP_RdgC	140..466	CDD:277364	98/311 (32%)
		PTZ00183	505..647	CDD:185503
		EF-hand_7	582..650	CDD:404394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810