DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD6 and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_113715.1	Gene:	Ppp1ca / 24668	RGDID:	3375	Length:	330	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	178/304 - (58%)
Similarity:	238/304 - (78%)	Gaps:	10/304 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LSNSEANADYRLPGALNLNDLLNKLMSFRRSKM-QRLPLLESEVNLLCTLARELFLDEPMLLNVP 78
            :|:||         .|||:.::.:|:..:.|:. :.:.|.|:|:..||..:||:||.:|:||.:.
  Rat     1 MSDSE---------KLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELE 56

  Fly    79 APIRVVGDIHGQFYDLLKILDQCGYPPQTRYLFLGDYVDRGKNSVETITLLLALRVKFPKHIYLL 143
            ||:::.||||||:||||::.:..|:||::.||||||||||||.|:|||.||||.::|:|::.:||
  Rat    57 APLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 121

  Fly   144 RGNHESQSVNRVYGFFDECKRRYTVKLWKTFVDCYNCMPVAAIISHRIFCCHGGLSPQLKELSNI 208
            |||||..|:||:|||:|||||||.:||||||.||:||:|:|||:..:||||||||||.|:.:..|
  Rat   122 RGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQI 186

  Fly   209 ESIARPTEVPETGLLCDLLWSDPDRYGFGWTSSDRGVSYLYGRDVLEKFLQKNDFDLVCRAHQVV 273
            ..|.|||:||:.||||||||||||:...||..:|||||:.:|.:|:.|||.|:|.||:|||||||
  Rat   187 RRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVV 251

  Fly   274 EDGYEFFAKRQLVTVFSAPNYCGLYDNAGASMGVDKDLVISFDI 317
            ||||||||||||||:||||||||.:|||||.|.||:.|:.||.|
  Rat   252 EDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQI 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	169/265 (64%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	166/260 (64%)
Ppp1ca	NP_113715.1	MPP_PP1_PPKL	8..298	CDD:277359	174/288 (60%)
Ppp1ca	NP_113715.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830