DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD6 and Ppef1

DIOPT Version :9

Sequence 1:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_011246120.1	Gene:	Ppef1 / 237178	MGIID:	1097157	Length:	676	Species:	Mus musculus

Alignment Length:	344	Identity:	98/344 - (28%)
Similarity:	157/344 - (45%)	Gaps:	57/344 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FAGQLSNSEANADYRLPGALNLNDLLNKLMSFRRSKMQRLPLLESEVNL-LCTLARELFLDEPML 74
            |.|.:...::....||...|...|:...|.:|::.:     :|.:...| :...||::....|..
Mouse   126 FLGLIEVPDSYDGPRLQFPLTFTDIHILLQAFKQQQ-----ILHAHYVLEVLFEARKVLKQMPNF 185

  Fly    75 LNV---PA-PIRVVGDIHGQFYDLLKILDQCGYPPQTR-YLFLGDYVDRGKNSVETITLLLALRV 134
            .:|   || .|.:.||:||:..||:.|..:.|.|.:.. |:|.||:||||.||:|.:.:||...:
Mouse   186 SHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFL 250

  Fly   135 KFPKHIYLLRGNHESQSVNRVYGFFDECKRRYTV---KLWKTFVDCYNCMPVAAIISHRIFCCHG 196
            .:|..::|.|||||...:|..|||..|..::|.:   |:.:...:.|..:|:..||.:.|...||
Mouse   251 VYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHG 315

  Fly   197 GLSPQLKELSNIESIAR-----------------------------------PTEVPETGL---- 222
            |:| :..:|:.:..:.|                                   |.:.|...|
Mouse   316 GIS-ESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPDKTPSEDLTKQE 379

  Fly   223 ---LCDLLWSDPDRYGFGWTSSDRGVSYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQ 284
               :.|:|||||......:.::.||....:|.||..|.|.||...::.|:|:...||||.....:
Mouse   380 WEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECKPDGYEVSHDGK 444

  Fly   285 LVTVFSAPNYCGLYDNAGA 303
            ::|||||.||.....|.||
Mouse   445 VITVFSASNYYEEGSNRGA 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	90/304 (30%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	89/301 (30%)
Ppef1	XP_011246120.1	MPP_RdgC	144..479	CDD:277364	94/326 (29%)
		PTZ00183	518..660	CDD:185503
		EF-hand_7	595..663	CDD:372618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810