DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD6 and pef-1

DIOPT Version :9

Sequence 1:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_741091.1	Gene:	pef-1 / 175257	WormBaseID:	WBGene00003969	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	103/320 - (32%)
Similarity:	159/320 - (49%)	Gaps:	36/320 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SNSEANADYRLPG---ALNLNDLLNKLMSFRRSKMQRLPLLESEVNLLCTLARELFLDEPMLLNV 77
            :|.:.:.:|:.|.   .|:...:...:.:|:.:|:    |....|.::...||::|...|.:..:
Worm   183 TNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKVNKV----LHPKYVLMILHEARKIFKAMPSVSRI 243

  Fly    78 PAPI----RVVGDIHGQFYDLLKILDQCGYPP-QTRYLFLGDYVDRGKNSVETITLLLALRVKFP 137
            ...|    .:.||:||:|.||..||.:.|||. ...|:|.||:||||..|:|.:.:|.||.:..|
Worm   244 STSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDP 308

  Fly   138 KHIYLLRGNHESQSVNRVYGFFDECKRRY---TVKLWKTFVDCYNCMPVAAIISHRIFCCHGGLS 199
            ..|||.|||||...:|..|||..|...:|   :..:.:...|.::.:|:|.||...||..|||:|
Worm   309 MSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGGIS 373

  Fly   200 PQ--LKELSNI-----ESIARP--------------TEVPETGLLCDLLWSDPDRYGFGWTSSDR 243
            .|  :.:|..|     :|:.||              ..|.|...:.|::||||.:....|.:..|
Worm   374 DQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNVFR 438

  Fly   244 GVSYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNYCGLYDNAGA 303
            |....:|.|:...||:|:.|.|:.|:|:...:||||......:|||||.||.....|.||
Worm   439 GGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGA 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	97/282 (34%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	96/279 (34%)
pef-1	NP_741091.1	MPP_RdgC	199..515	CDD:277364	100/304 (33%)
		PP2Ac	218..514	CDD:197547	97/281 (35%)
		EFh	634..699	CDD:238008
		EF-hand_7	634..698	CDD:290234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910