DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and AT1G48120

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_175246.2	Gene:	AT1G48120 / 841230	AraportID:	AT1G48120	Length:	1340	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	151/533 - (28%)
Similarity:	220/533 - (41%)	Gaps:	141/533 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 GFALQDGVSAVKADPAYLKGYYRRAAA----HMSLGKFKQALCDFEFVAKCR-PNDKDAKLKFTE 159
            |||.|..|..|.|       .:.|:.|    .:::|..:|.|.|  .|..|. ....:|.|....
plant   457 GFAFQVLVQRVAA-------IHARSRASLEEELTVGSARQTLQD--IVDMCAGALQLNAPLGSLS 512

  Fly   160 CNKIVKMRAFERAIAVDKPEKTL-------SEM----YSDMENITIEDDYKGPQLE--------- 204
            ...:.:....|..:.:.:|..|:       .||    .:|||   |:|......||
plant   513 NGSVAQAPTPEPFLMLPQPTPTIIPQKPMGGEMVCLPLNDME---IDDGLAAEPLELMPPVQDIG 574

  Fly   205 -----------------DGKVTLKFMKELMEHYK-AQKRL-----HRKFAYKILCEIDTY----M 242
                             .||:|..::.|:|..:. :.|.|     .....:.:|.|:..:    :
plant   575 CEQSLSSVSQKPLFWPSGGKLTFSWVCEVMLVFDWSSKNLPPCEFSSVLPFNVLDELVLFASKIL 639

  Fly   243 RAQPSLVDITVPDEEK--FTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECI 305
            :.:|:.|.|   |.||  ..:.||:|||.:||:.:.:..|.|.....|:|||::||.|::.:|..
plant   640 KKEPNCVRI---DSEKAEVVVVGDLHGQLHDLLYLMQDAGFPDGDRFYVFNGNYVDIGAWGLETF 701

  Fly   306 FTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIF---TQVFNWLPLCHCIN 367
            ..|..:|:|.|...:|.||:|||.:...||||..||..||....|.::   .:.|..|||...|.
plant   702 LLLLSWKVLLPARVYLLRGSHESESCTSMYGFKNEVLTKYGDKGAAVYKKCLECFQLLPLASVIA 766

  Fly   368 QKILVMHGGLF-----------------------STEDVTLDHIRRIE---------------RN 394
            .|:...|||||                       .|::..||...|.|               |.
plant   767 GKVYTAHGGLFRDVSSFLSDKQERNRKRKRTQKKQTDNTVLDTEDRSESLPLGSLKDLSKVKRRV 831

  Fly   395 CQPPEEG---LMCELLWSDPQQWMGLGQSK-RGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDM- 454
            ..||.||   :..::|||||.:..||..:| ||:|:.:|||.|.||.:||||.:|||.....|.
plant   832 IDPPTEGSNLIPGDILWSDPSKDTGLFLNKERGIGLLWGPDCTAKFLQDNNLKWIIRGKGAPDER 896

  Fly   455 -----------GYEVAHNGKCITVFSAPN---YCDT---MGNMGAFITI---TGNNLKPNYKSFE 499
                       ||...|.| .||:||||:   :.||   ..|..|:|.:   ....||  ::..|
plant   897 AKRDDLAPMNGGYAEDHEG-LITLFSAPDHPQFQDTEERHNNKAAYIILQIPECEELK--FQPLE 958

  Fly   500 AV-PHPDVKPMAY 511
            || |.|  |..||
plant   959 AVSPRP--KAEAY 969

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150	7/13 (54%)
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809	6/11 (55%)
		MPP_PP5_C	198..513	CDD:277362	124/419 (30%)
		PP2Ac	226..502	CDD:197547	111/353 (31%)
AT1G48120	NP_175246.2	PMD	78..435	CDD:287502
		MPP_PP7	589..971	CDD:163661	122/389 (31%)
		PP2Ac	631..961	CDD:197547	107/335 (32%)
		Ehrlichia_rpt	981..>1325	CDD:118064
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45668
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.870