DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpD3 and PP5.2

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001031534.1	Gene:	PP5.2 / 818881	AraportID:	AT2G42810	Length:	538	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	275/532 - (51%)
Similarity:	353/532 - (66%)	Gaps:	55/532 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 TKAE-LDFAAAEQYKNQGNEMLKTKEFSKAIDMYTKAIELHPNSAIYYANRSLAHLRQESFGFAL 103
            ||.| .|.:.||::|:|.||..|..::|.|||:|||||||:.|:|:|:|||:.||.:.|.:|.|:
plant     3 TKNENSDVSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAI 67

  Fly   104 QDGVSAVKADPAYLKGYYRRAAAHMSLGKFKQALCDFEFVAKCRPNDKDAKLKFTECNKIVKMRA 168
            ||...|::.|..|.||||||.||::::||||.||.||:.|.:..|||.||..|..||.|.|....
plant    68 QDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKECEKAVMKLK 132

  Fly   169 FERAIAV------------------------DKPEKT------------------LSEMYSDMEN 191
            ||.||:|                        ..|.||                  .:|:...:.:
plant   133 FEEAISVPVSERRSVAESIDFHTIGNKPRSSSMPTKTALAAVVAAVMVVAVRGFATTEILMVLVS 197

  Fly   192 IT------------IEDDYKGPQLEDGKVTLKFMKELMEHYKAQKRLHRKFAYKILCEIDTYMRA 244
            :.            :|..|.|.::|..:|||.|:|.:||.:|.||.||:::||:|:.:....:.|
plant   198 VVLGTFWWGSFSGKVEPQYSGARIEGEEVTLDFVKTMMEDFKNQKTLHKRYAYQIVLQTRQILLA 262

  Fly   245 QPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLF 309
            .||||||:||..:..|:|||:|||||||:||||:||||||:||||||||||||||||||.|.|||
plant   263 LPSLVDISVPHGKHITVCGDVHGQFYDLLNIFELNGLPSEENPYLFNGDFVDRGSFSVEIILTLF 327

  Fly   310 GFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVMH 374
            .||.:.|:..:||||||||.:||::|||.|||.:|.:....|:|.:||.:|||.|.||.|:.|:|
plant   328 AFKCMCPSSIYLARGNHESKSMNKIYGFEGEVRSKLSEKFVDLFAEVFCYLPLAHVINGKVFVVH 392

  Fly   375 GGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMGLGQSKRGVGIQFGPDVTEKFCKD 439
            |||||.:.|.|..||.|:|.|:||||||||||||||||...|.|.||||||:.||.|||::|.:|
plant   393 GGLFSVDGVKLSDIRAIDRFCEPPEEGLMCELLWSDPQPLPGRGPSKRGVGLSFGGDVTKRFLQD 457

  Fly   440 NNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVPHP 504
            ||||.::|||||||.||||.|:||.|||||||||||.|||.||||.....::|||..:|.|||||
plant   458 NNLDLLVRSHEVKDEGYEVEHDGKLITVFSAPNYCDQMGNKGAFIRFEAPDMKPNIVTFSAVPHP 522

  Fly   505 DVKPMAYANSLM 516
            |||||||||:.:
plant   523 DVKPMAYANNFL 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150	32/64 (50%)
		TPR_1	49..81	CDD:278916	18/31 (58%)
		TPR repeat	49..77	CDD:276809	15/27 (56%)
		TPR repeat	82..112	CDD:276809	13/29 (45%)
		MPP_PP5_C	198..513	CDD:277362	198/314 (63%)
		PP2Ac	226..502	CDD:197547	174/275 (63%)
PP5.2	NP_001031534.1	TPR_11	12..77	CDD:290150	32/64 (50%)
		TPR	13..46	CDD:197478	18/32 (56%)
		TPR repeat	13..41	CDD:276809	15/27 (56%)
		TPR_17	35..68	CDD:290167	18/32 (56%)
		TPR repeat	46..76	CDD:276809	13/29 (45%)
		TPR_16	53..115	CDD:290168	30/61 (49%)
		TPR_1	81..114	CDD:278916	18/32 (56%)
		TPR repeat	81..109	CDD:276809	17/27 (63%)
		MPP_PP5_C	216..531	CDD:277362	198/314 (63%)
		PP2Ac	244..520	CDD:197547	174/275 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	280	1.000	Domainoid score	I400
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4550
Inparanoid	1	1.050	532	1.000	Inparanoid score	I278
OMA	1	1.010	-	-		QHG54071
OrthoDB	1	1.010	-	-		D671536at2759
OrthoFinder	1	1.000	-	-		FOG0005066
OrthoInspector	1	1.000	-	-		oto2904
orthoMCL	1	0.900	-	-		OOG6_102598
Panther	1	1.100	-	-	LDO	PTHR45668
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3586
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840