DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ppp3ca

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001185479.1	Gene:	ppp3ca / 794574	ZFINID:	ZDB-GENE-091113-24	Length:	521	Species:	Danio rerio

Alignment Length:	314	Identity:	120/314 - (38%)
Similarity:	173/314 - (55%)	Gaps:	25/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 DGKVTLKFMKELMEHYKAQKRLHRKFAYKILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQF 269
            :||..:..:|   .|...:.|:....|.:|:.|..:.:|.:.:::||..|    .|:||||||||
Zfish    37 EGKPRVDLLK---AHLTKEGRVEETVALRIINEGASILRQEKTMLDIEAP----VTVCGDIHGQF 94

  Fly   270 YDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQM 334
            :|||.:||:.|.|:... |||.||:||||.||:||:..|:..|:|||...||.|||||..::.:.
Zfish    95 FDLMKLFEVGGSPATTR-YLFLGDYVDRGYFSIECVLYLWSLKILYPKTLFLLRGNHECRHLTEY 158

  Fly   335 YGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPE 399
            :.|..|...||:..:.|.....|:.|||...:||:.|.:|||| |.|..|||.|::::|..:||.
Zfish   159 FTFKQECKIKYSEQVYDSCMDAFDCLPLAALMNQQFLCVHGGL-SPEIQTLDDIKKLDRFKEPPA 222

  Fly   400 EGLMCELLWSDPQQWMGLGQSK--------RGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGY 456
            .|.||:||||||.:..|..:|:        ||....:.......|.::|||..|||:||.:|.||
Zfish   223 FGPMCDLLWSDPLEDFGNEKSQEYFSHNTVRGCSYFYSYPAVCDFLQNNNLLSIIRAHEAQDAGY 287

  Fly   457 EVAHNGK------CITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVPHP 504
            .:....:      .||:||||||.|...|..|.:....|.:  |.:.|...|||
Zfish   288 RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHP 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	120/314 (38%)
		PP2Ac	226..502	CDD:197547	112/289 (39%)
ppp3ca	NP_001185479.1	MPP_PP2B	40..344	CDD:277361	118/311 (38%)
ppp3ca	NP_001185479.1	PP2Ac	59..328	CDD:197547	110/274 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810