DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ppp3ccb

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_005155370.1	Gene:	ppp3ccb / 565241	ZFINID:	ZDB-GENE-070112-1102	Length:	511	Species:	Danio rerio

Alignment Length:	355	Identity:	126/355 - (35%)
Similarity:	182/355 - (51%)	Gaps:	40/355 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 KMRAFERAI-AVDKPEKTLSEMYSDMENITIEDDYKGPQLEDGKVTLKFMKELMEHYKAQKRLHR 228
            |....||.: ||..|..|         .:|:::.|     ||||..::.:|   .|...:.||..
Zfish     8 KQSTTERLVKAVPYPPTT---------RLTMKELY-----EDGKPKVELLK---SHLVKEGRLEE 55

  Fly   229 KFAYKILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGD 293
            ..|.:|:.:....:|.:..::::..|    .|:|||:||||:|||.:||:.|.| ....|||.||
Zfish    56 DVALRIINDGANILRHEKCMLEVEAP----ITVCGDVHGQFFDLMKLFEVGGSP-HNTRYLFLGD 115

  Fly   294 FVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFN 358
            :||||.||:||:..|:..|:.:|...||.|||||..::.:.:.|..|...|||..:.|...:.|:
Zfish   116 YVDRGYFSIECVLYLWALKINHPTTLFLLRGNHECRHLTEYFTFKQECKIKYTERVYDACMEAFD 180

  Fly   359 WLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMG------- 416
            .|||...:||:.|.:|||| |.|...||.||:::|..:||..|.||:||||||.:..|
Zfish   181 CLPLAALLNQQFLCVHGGL-SPEVTCLDDIRKLDRFKEPPAFGPMCDLLWSDPGEDYGSEKTSEH 244

  Fly   417 -LGQSKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGK------CITVFSAPNYC 474
             ...|.||....:.......|..:|||..:||:||.:|.||.:....:      .||:||||||.
Zfish   245 FCHNSVRGCSYFYSYPAVCDFLTNNNLLSVIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYL 309

  Fly   475 DTMGNMGAFITITGNNLKPNYKSFEAVPHP 504
            |...|..|.:....|.:  |.:.|...|||
Zfish   310 DVYNNKAAVLKYENNVM--NIRQFNCSPHP 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	118/321 (37%)
		PP2Ac	226..502	CDD:197547	107/289 (37%)
ppp3ccb	XP_005155370.1	MPP_PP2B	38..342	CDD:277361	113/311 (36%)
ppp3ccb	XP_005155370.1	PP2Ac	55..326	CDD:197547	104/276 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900