DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ppp3cca

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_005171933.1	Gene:	ppp3cca / 557926	ZFINID:	ZDB-GENE-030829-36	Length:	508	Species:	Danio rerio

Alignment Length:	368	Identity:	125/368 - (33%)
Similarity:	187/368 - (50%)	Gaps:	47/368 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 KDAKLKFTECNKIVKMRAFERAIAVDKPEKTLSEMYSDMENITIEDDYKGPQLEDGKVTLKFMKE 215
            |:.|.|.:...:|:|        .|..|..         :.:||:|.|     .|||...:.:|
Zfish     4 KEPKEKLSTTERIIK--------TVPLPPH---------QRLTIKDLY-----VDGKPNTELLK- 45

  Fly   216 LMEHYKAQKRLHRKFAYKILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEING 280
              .|...:.|:....|.:|:.:....:|.:..::::..|    .|:|||:||||:|||.:||:.|
Zfish    46 --NHLIKEGRVEEDAALRIINDGANILRQEKCMLEVEAP----ITVCGDVHGQFFDLMKLFEVGG 104

  Fly   281 LPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKY 345
            .| :...|||.||:||||.||:||:..|:..|:.:||..||.|||||..::.:.:.|..|...||
Zfish   105 SP-DNTRYLFLGDYVDRGYFSIECVLFLWTLKINHPNTLFLLRGNHECRHLTEYFTFKQECKIKY 168

  Fly   346 TSAMADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSD 410
            :..:.|...:.|:.|||...:||:.|.:|||| |.|...||.||:::|..:||..|.||:|:|:|
Zfish   169 SERVYDACMEAFDCLPLAALLNQQFLCVHGGL-SPEINCLDDIRKLDRFKEPPAFGPMCDLIWAD 232

  Fly   411 PQQWMGLGQ--------SKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGK---- 463
            |.:..|..:        |.||....|.......|..:|||..:||:||.:|.||.:....:
Zfish   233 PGEDYGSEKTAEHFNHNSVRGCSYFFSYAAVCDFLTNNNLLSVIRAHEAQDAGYRMYRKSQTTGF 297

  Fly   464 --CITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVPHP 504
              .||:||||||.|...|..|.:....|.:  |.:.|...|||
Zfish   298 PSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHP 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	115/321 (36%)
		PP2Ac	226..502	CDD:197547	105/289 (36%)
ppp3cca	XP_005171933.1	MPP_PP2B	39..343	CDD:277361	111/311 (36%)
ppp3cca	XP_005171933.1	PP2Ac	59..327	CDD:197547	103/273 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900