DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ppp6c

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001017110.1	Gene:	ppp6c / 549864	XenbaseID:	XB-GENE-1017127	Length:	305	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	115/272 - (42%)
Similarity:	155/272 - (56%)	Gaps:	9/272 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 KILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDR 297
            |.||:....:..:.|.|.   |.....|:|||||||||||..:|...|...:.| |:|.||||||
Frog    25 KRLCDYVCDLLLEESNVQ---PVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDR 85

  Fly   298 GSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIF-TQVFNWLP 361
            |.:|:|....|...|..:|:...|.||||||..:.|:|||..|...||.:|.|..: |:||:.|.
Frog    86 GYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLT 150

  Fly   362 LCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMGLGQSKRGVGI 426
            :...|:::||.:|||| |.:..|||.||.||||.:.|.:|..|:|:||||:.......|.||.|.
Frog   151 VAALIDEQILCVHGGL-SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGW 214

  Fly   427 QFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITG-NN 490
            .||..||.:|...|||..|.|:|::...||:...:.|.:||:||||||...||:.:.:.... |.
Frog   215 LFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNT 279

  Fly   491 LKPNYKSFEAVP 502
            .:|  |.|.|||
Frog   280 REP--KLFRAVP 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	115/272 (42%)
		PP2Ac	226..502	CDD:197547	113/270 (42%)
ppp6c	NP_001017110.1	MPP_PP2A_PP4_PP6	5..289	CDD:277360	113/270 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910