DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpD3 and PpD6

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	124/349 - (35%)
Similarity:	186/349 - (53%)	Gaps:	28/349 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 IAVDKPEKTLSEMY--SDMENITIEDDYKGPQLEDGKVTLK-FMKELM--EHYKAQKRLHRKFAY 232
            :|||    ||..::  ..:.|.....||:.|    |.:.|. .:.:||  ...|.|:....:...
  Fly     1 MAVD----TLHSLHFAGQLSNSEANADYRLP----GALNLNDLLNKLMSFRRSKMQRLPLLESEV 57

  Fly   233 KILCEI--DTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFV 295
            .:||.:  :.:: .:|.|:::..|    ..:.||||||||||:.|.:..|.|.:.. |||.||:|
  Fly    58 NLLCTLARELFL-DEPMLLNVPAP----IRVVGDIHGQFYDLLKILDQCGYPPQTR-YLFLGDYV 116

  Fly   296 DRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWL 360
            |||..|||.|..|...::.:|.|.:|.||||||.::|::|||..|...:||..:...|...:|.:
  Fly   117 DRGKNSVETITLLLALRVKFPKHIYLLRGNHESQSVNRVYGFFDECKRRYTVKLWKTFVDCYNCM 181

  Fly   361 PLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQW-MGLGQSKRGV 424
            |:...|:.:|...|||| |.:...|.:|..|.|..:.||.||:|:||||||.:: .|...|.|||
  Fly   182 PVAAIISHRIFCCHGGL-SPQLKELSNIESIARPTEVPETGLLCDLLWSDPDRYGFGWTSSDRGV 245

  Fly   425 GIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGN 489
            ...:|.||.|||.:.|:.|.:.|:|:|.:.|||.....:.:|||||||||....|.||.:.:.
  Fly   246 SYLYGRDVLEKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNYCGLYDNAGASMGVD-- 308

  Fly   490 NLKPNYKSFEAVPHPDVKPMAYAN 513
              |....||: :...|::.:...|
  Fly   309 --KDLVISFD-IQRGDIRRIVVRN 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	116/320 (36%)
		PP2Ac	226..502	CDD:197547	107/278 (38%)
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	107/277 (39%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	105/271 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438824
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740