DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and mts

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001285724.1	Gene:	mts / 45959	FlyBaseID:	FBgn0004177	Length:	309	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	116/302 - (38%)
Similarity:	173/302 - (57%)	Gaps:	11/302 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 LEDGKVTLKFMKELMEHYKAQKRLHRKFAYKILCE-IDTYMRAQPSLVDITVPDEEKFTICGDIH 266
            :|| |.|.|.:.:.:|......:| .:...:.||: ....:..:.::.::..|    .|:|||:|
  Fly     1 MED-KATTKDLDQWIEQLNECNQL-TETQVRTLCDKAKEILSKESNVQEVKCP----VTVCGDVH 59

  Fly   267 GQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINM 331
            |||:|||.:|.|.|...:.| |||.||:||||.:|||.:..|...|:.|.....:.||||||..:
  Fly    60 GQFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQI 123

  Fly   332 NQMYGFTGEVTAKYTSA-MADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNC 395
            .|:|||..|...||.:| :...||.:|::|||...::.:|..:||||..:.| :|||||.::|..
  Fly   124 TQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSID-SLDHIRALDRLQ 187

  Fly   396 QPPEEGLMCELLWSDPQQWMGLGQSKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAH 460
            :.|.||.||:||||||....|.|.|.||.|..||.|::|.|...|.|..:.|:|::...||...|
  Fly   188 EVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCH 252

  Fly   461 NGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVP 502
            :...:|:|||||||...||..|.:.: .::||.::..|:..|
  Fly   253 DRNVVTIFSAPNYCYRCGNQAALMEL-DDSLKFSFLQFDPAP 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	116/302 (38%)
		PP2Ac	226..502	CDD:197547	109/277 (39%)
mts	NP_001285724.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	110/291 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438805
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740