DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpD3 and Pp1alpha-96A

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001262919.1	Gene:	Pp1alpha-96A / 42922	FlyBaseID:	FBgn0003134	Length:	327	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	114/271 - (42%)
Similarity:	163/271 - (60%)	Gaps:	11/271 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 AQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTL 308
            :||.|:::..|    ..||||||||:|||:.:||..|.|.|.| |||.||:||||..|:|.|..|
  Fly    46 SQPILLELEAP----LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLL 105

  Fly   309 FGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVM 373
            ..:|:.|..:|||.|||||..::|::|||..|...:||..:...||..||.||:...:::||...
  Fly   106 LAYKIKYAENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDCFNCLPVAAIVDEKIFCC 170

  Fly   374 HGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDP-QQWMGLGQSKRGVGIQFGPDVTEKFC 437
            |||| |.:..:::.||||.|....|::||:|:|||||| :..||.|::.|||...||.:|..||.
  Fly   171 HGGL-SPDLSSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVGKFL 234

  Fly   438 KDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVP 502
            :.:..|.|.|:|:|.:.|||.....:.:|:|||||||....|.||.:::....:    .||:.:.
  Fly   235 QKHEFDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDDTLM----CSFQILK 295

  Fly   503 HPDVKPMAYAN 513
            ..|.:...|.|
  Fly   296 PADKRRFVYPN 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	113/269 (42%)
		PP2Ac	226..502	CDD:197547	111/258 (43%)
Pp1alpha-96A	NP_001262919.1	MPP_PP1_PPKL	6..296	CDD:277359	111/259 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740