DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ppp2cb

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_998458.1	Gene:	ppp2cb / 406582	ZFINID:	ZDB-GENE-040426-2487	Length:	309	Species:	Danio rerio

Alignment Length:	300	Identity:	118/300 - (39%)
Similarity:	170/300 - (56%)	Gaps:	10/300 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 DGKVTLKFMKELMEHYKAQKRLHRKFAYKILCE-IDTYMRAQPSLVDITVPDEEKFTICGDIHGQ 268
            |.|...|.:.:.:|.....|:|... ..:.||| ....:..:.::.::..|    .|:|||:|||
Zfish     2 DDKAFTKELDQWVEQLNECKQLTEN-QVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQ 61

  Fly   269 FYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQ 333
            |:|||.:|.|.|...:.| |||.||:||||.:|||.:..|...|:.||....:.||||||..:.|
Zfish    62 FHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQ 125

  Fly   334 MYGFTGEVTAKYTSA-MADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQP 397
            :|||..|...||.:| :...||.:|::|||...::.:|..:||||..:.| ||||||.::|..:.
Zfish   126 VYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSID-TLDHIRALDRLQEV 189

  Fly   398 PEEGLMCELLWSDPQQWMGLGQSKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNG 462
            |.||.||:||||||....|.|.|.||.|..||.|::|.|...|.|..:.|:|::...||...|:.
Zfish   190 PHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDR 254

  Fly   463 KCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVP 502
            ..:|:|||||||...||..|.:.: .:.||.::..|:..|
Zfish   255 NVVTIFSAPNYCYRCGNQAAIMEL-DDTLKYSFLQFDPAP 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	117/299 (39%)
		PP2Ac	226..502	CDD:197547	112/277 (40%)
ppp2cb	NP_998458.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	114/291 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910