DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpD3 and ppp4c

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_988943.1	Gene:	ppp4c / 394540	XenbaseID:	XB-GENE-970535	Length:	307	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	125/286 - (43%)
Similarity:	161/286 - (56%)	Gaps:	20/286 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 AYKILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFV 295
            |.:||.|.....|     ||..|      |:|||||||||||..:|.:.|...|.| |||.||||
Frog    32 AREILVEESNVQR-----VDSPV------TVCGDIHGQFYDLKELFRVGGDVPETN-YLFMGDFV 84

  Fly   296 DRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIF-TQVFNW 359
            |||.:|||....|...|:.||:...|.||||||..:.|:|||..|...||.|.....: |::|::
Frog    85 DRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDY 149

  Fly   360 LPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMGLGQSKRGV 424
            |.|...|:.||..:|||| |....|||.||.|:|..:.|.:|.||:||||||:...|.|.|.||.
Frog   150 LSLSAIIDGKIFCVHGGL-SPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGA 213

  Fly   425 GIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGN 489
            |..||.||..:|...||:|.|.|:|::...||:...|...:||:||||||...||:.|.:.: ..
Frog   214 GYLFGSDVVAQFNAANNIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL-DE 277

  Fly   490 NLKPNYKSFEAVPH-----PDVKPMA 510
            :|:..:..|||.|.     |..||:|
Frog   278 HLQKEFIIFEAAPQETRGIPSKKPVA 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	125/286 (44%)
		PP2Ac	226..502	CDD:197547	120/271 (44%)
ppp4c	NP_988943.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	120/271 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910