DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and PpN58A

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_477384.1	Gene:	PpN58A / 37493	FlyBaseID:	FBgn0025573	Length:	324	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	103/243 - (42%)
Similarity:	137/243 - (56%)	Gaps:	7/243 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 QPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLF 309
            ||:|::|..|    ..:.||||||:.:|:..||.||.|.: :.||..||:||||..|:|.:..|.
  Fly    62 QPTLLEIPAP----INLLGDIHGQYLNLLRYFESNGYPPD-SVYLLLGDYVDRGKQSIETLTLLL 121

  Fly   310 GFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVMH 374
            ..|..||..|:|.|||||..::|..|||..|...:||..:...|...:|.|||...|.:.|...|
  Fly   122 ALKARYPTKFYLLRGNHECSSINHFYGFYDECKRRYTVKLWRTFVDCYNCLPLAAIIEENIFCCH 186

  Fly   375 GGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQ-QWMGLGQSKRGVGIQFGPDVTEKFCK 438
            ||| |....::..||.|.|..:.||.||:|::|||||. :.||.|.::|||...||.||...|..
  Fly   187 GGL-SPHLFSMQQIREIRRPIEIPESGLICDILWSDPDLRIMGWGPNERGVSHTFGSDVVSAFLH 250

  Fly   439 DNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITI 486
            ...|:.|.|.|:|.:.|||.....:.||:|||||||....|.||.:.|
  Fly   251 RFKLNLICRGHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMCI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	103/243 (42%)
		PP2Ac	226..502	CDD:197547	103/243 (42%)
PpN58A	NP_477384.1	PTZ00480	22..311	CDD:185658	103/243 (42%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:301300	103/243 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438823
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830