DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ppp1cab

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_997875.1	Gene:	ppp1cab / 327301	ZFINID:	ZDB-GENE-030131-5512	Length:	332	Species:	Danio rerio

Alignment Length:	272	Identity:	111/272 - (40%)
Similarity:	166/272 - (61%)	Gaps:	11/272 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 AQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTL 308
            :||.|:::..|    ..||||:|||:|||:.:||..|.|.|.| |||.||:||||..|:|.|..|
Zfish    48 SQPILLELEAP----LKICGDVHGQYYDLLRLFEYGGYPPESN-YLFLGDYVDRGKQSLETICLL 107

  Fly   309 FGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVM 373
            ..:|:.||.:|||.|||||..::|::|||..|...:|...:...||..||.||:...:::||...
Zfish   108 LAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIVDEKIFCC 172

  Fly   374 HGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDP-QQWMGLGQSKRGVGIQFGPDVTEKFC 437
            |||| |.:..:::.|||:.|....|::||:|:|||:|| :..||.|::.|||...||.||..||.
Zfish   173 HGGL-SPDLQSMEQIRRVMRPTDVPDQGLLCDLLWADPDKDVMGWGENDRGVSFTFGSDVVAKFL 236

  Fly   438 KDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVP 502
            ..:::|.|.|:|:|.:.|||.....:.:|:|||||||....|.||.:::....:    .||:.:.
Zfish   237 HKHDMDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLM----CSFQILK 297

  Fly   503 HPDVKPMAYANS 514
            ..:.|.::|..:
Zfish   298 PAEKKVLSYGGA 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	111/269 (41%)
		PP2Ac	226..502	CDD:197547	109/258 (42%)
ppp1cab	NP_997875.1	PTZ00480	6..321	CDD:185658	111/272 (41%)
ppp1cab	NP_997875.1	MPP_PP1_PPKL	8..298	CDD:277359	109/259 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810