DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and Pp2B-14D

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001245715.1	Gene:	Pp2B-14D / 32624	FlyBaseID:	FBgn0011826	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	124/346 - (35%)
Similarity:	182/346 - (52%)	Gaps:	29/346 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 AVDKPEKTLSEM-YSDMENITIEDDYKGPQLEDGKVTLKFMKELMEHYKAQKRLHRKFAYKILCE 237
            ||:..|:.:..: :.....:|:.:.:   ....||...:.:|   :|:..:.|:....|.||:.:
  Fly    75 AVNTKERVVDSVPFPPSHKLTLAEVF---DQRTGKPNHELLK---QHFILEGRIEEAPALKIIQD 133

  Fly   238 IDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSV 302
            ....:|.:.:::||..|    .|:||||||||||||.:||:.|.|: ...|||.||:||||.||:
  Fly   134 GAALLRQEKTMIDIEAP----VTVCGDIHGQFYDLMKLFEVGGSPA-STKYLFLGDYVDRGYFSI 193

  Fly   303 ECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCIN 367
            ||:..|:..|:.||...||.|||||..::.:.:.|..|...||:..:.|.....|:.|||...:|
  Fly   194 ECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMN 258

  Fly   368 QKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMG--------LGQSKRGV 424
            |:.|.:|||| |.|...|:.|||::|..:||..|.||:||||||.:..|        ...|.||.
  Fly   259 QQFLCVHGGL-SPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGC 322

  Fly   425 GIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGK------CITVFSAPNYCDTMGNMGAF 483
            ...:.......|.::|||..|||:||.:|.||.:....:      .||:||||||.|...|..|.
  Fly   323 SYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAV 387

  Fly   484 ITITGNNLKPNYKSFEAVPHP 504
            :....|.:  |.:.|...|||
  Fly   388 LKYENNVM--NIRQFNCSPHP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	120/321 (37%)
		PP2Ac	226..502	CDD:197547	112/289 (39%)
Pp2B-14D	NP_001245715.1	MPP_PP2B	107..411	CDD:277361	118/311 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438826
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740