DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ZK938.1

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_496117.1	Gene:	ZK938.1 / 191467	WormBaseID:	WBGene00014158	Length:	327	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	107/267 - (40%)
Similarity:	152/267 - (56%)	Gaps:	13/267 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 ILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRG 298
            ::.|....:.||.::|::..|    ..:|||||||:.||:.||.....|.::| |||.||:||||
Worm    34 VIEECKDILSAQATMVEVQAP----IAVCGDIHGQYTDLLRIFNRCSFPPDQN-YLFLGDYVDRG 93

  Fly   299 SFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLC 363
            ...:|.|..|..:|:.|||.||:.|||||..::|:.|||..|...:|:.|:.:.|..:||.||||
Worm    94 RQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLC 158

  Fly   364 HCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQ-QWMGLGQSKRGVGIQ 427
            ..|:.:|..||||| |.|.|:...:.:|.|...||...|..:|||:||: ...|.|::.|||...
Worm   159 AMISGRIFCMHGGL-SPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYI 222

  Fly   428 FGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTM-GNMGAFIT-----I 486
            ||.:|.:.|.:..|:|.|.|.|:|...|||...:.:.:|:||||.||... .|.|..|.     |
Worm   223 FGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLII 287

  Fly   487 TGNNLKP 493
            :...|||
Worm   288 SFEILKP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	107/267 (40%)
		PP2Ac	226..502	CDD:197547	107/267 (40%)
ZK938.1	NP_496117.1	MPP_superfamily	3..294	CDD:301300	105/265 (40%)
ZK938.1	NP_496117.1	PP2Ac	28..296	CDD:197547	107/267 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900