DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and Ppp3cb

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_006518770.1	Gene:	Ppp3cb / 19056	MGIID:	107163	Length:	534	Species:	Mus musculus

Alignment Length:	358	Identity:	126/358 - (35%)
Similarity:	188/358 - (52%)	Gaps:	46/358 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 NKIVKMRAFERAIAVDKPEKTLSEMYSDMENITIEDDYKGPQLEDGKVTLKFMKELMEHYKAQKR 225
            :::||      |:......:..||...||:.|...|..|...:::|                  |
Mouse    24 DRVVK------AVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLVKEG------------------R 64

  Fly   226 LHRKFAYKILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLF 290
            :..:.|.:|:.|....:|.:.:::::..|    .|:||||||||:|||.:||:.|.|:... |||
Mouse    65 VDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDLMKLFEVGGSPANTR-YLF 124

  Fly   291 NGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMADIFTQ 355
            .||:||||.||:||:..|:..|:|||:..||.|||||..::.:.:.|..|...||:..:.:...:
Mouse   125 LGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACME 189

  Fly   356 VFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMGLGQS 420
            .|:.|||...:||:.|.:|||| |.|..|||.|||::|..:||..|.||:||||||.:..|..:|
Mouse   190 AFDSLPLAALLNQQFLCVHGGL-SPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKS 253

  Fly   421 K--------RGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGK------CITVFSAP 471
            :        ||....:......:|.::|||..|||:||.:|.||.:....:      .||:||||
Mouse   254 QEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318

  Fly   472 NYCDTMGNMGAFITITGNNLKPNYKSFEAVPHP 504
            ||.|...|..|.:....|.:  |.:.|...|||
Mouse   319 NYLDVYNNKAAVLKYENNVM--NIRQFNCSPHP 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	117/321 (36%)
		PP2Ac	226..502	CDD:197547	111/289 (38%)
Ppp3cb	XP_006518770.1	MPP_PP2B	50..354	CDD:277361	118/326 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810