DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and T16G12.7

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_499229.1	Gene:	T16G12.7 / 188557	WormBaseID:	WBGene00011808	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	92/262 - (35%)
Similarity:	143/262 - (54%)	Gaps:	23/262 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 DTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRG--SFS 301
            |.:|: |.:::::..|    ..||||:|||:.|::.:|:..|.|...| |||.||:||||  |..
Worm    54 DVFMK-QGAMLELEAP----VKICGDVHGQYSDVLRLFDRGGFPPLVN-YLFLGDYVDRGQQSLE 112

  Fly   302 VECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKY----TSAMADIFTQVFNWLPL 362
            |.|:|  ..:|:.:|.:||:.|||||..::|::|||..||..||    .:.|.:.|...|.::|.
Worm   113 VACLF--LAYKVKFPGNFFMLRGNHECGSINRVYGFLDEVQRKYGAKGGTTMWNCFQICFAYMPY 175

  Fly   363 CHCINQKILVMHGGLFSTEDVTLDHIRRIERN----CQPPEEGLMCELLWSDPQQWM-GLGQSKR 422
            ...::.:||.||||: |.....|:.:|.::|.    ..|..|   .::|||||...: ....|.|
Worm   176 TALVSGRILCMHGGI-SKRMNNLNQLRNLQRPVLEVANPSVE---IDILWSDPDSTVDDFVDSTR 236

  Fly   423 GVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITIT 487
            |||..||...........::|.:.|:|:|...|||..:|.:.:|:||||:||....|..|.:.:.
Worm   237 GVGQVFGAKALTAIMNKLDVDLVARAHQVVQDGYEFFNNKRLVTIFSAPHYCGEFDNAAAMMNVD 301

  Fly   488 GN 489
            .|
Worm   302 KN 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	92/262 (35%)
		PP2Ac	226..502	CDD:197547	92/262 (35%)
T16G12.7	NP_499229.1	MPP_superfamily	18..313	CDD:301300	92/262 (35%)
T16G12.7	NP_499229.1	PP2Ac	40..313	CDD:197547	92/262 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810