DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and F49E11.7

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_502500.3	Gene:	F49E11.7 / 186051	WormBaseID:	WBGene00009893	Length:	384	Species:	Caenorhabditis elegans

Alignment Length:	332	Identity:	102/332 - (30%)
Similarity:	161/332 - (48%)	Gaps:	47/332 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 FMKELMEHYKAQKRLHRKFAYKILCE-IDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNI 275
            |:|..: :|:.|.  :.|:....|.| ::..:....:|..|:.|    .||.||||||:.||:.:
Worm    19 FVKNWV-NYRQQS--YTKYELMQLIESVEAALSVDDTLAKISPP----VTIVGDIHGQYPDLVRV 76

  Fly   276 F-EINGLPSEK---------NPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESIN 330
            . ..|.....|         :.::|.||:||||..|:|||..:|..|::||.::.|.|||||:.:
Worm    77 LCNQNSKEDAKKKAAYGFCNSRFVFLGDYVDRGHHSIECISLVFALKVVYPTNYILLRGNHETKS 141

  Fly   331 MNQMYGFTGEVTAKYTS----AMADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRI 391
            :|..|||..|:..:...    .:.:.|...|:|:||...:..|||.||||: |.:..:|..|..|
Worm   142 INYTYGFREELVNRLGPIDGFEIWERFNVAFSWMPLACLVGHKILCMHGGI-SPKLHSLKEINEI 205

  Fly   392 ERNCQPPEE----GLMCELLWSDPQQWMG----------LGQSKRGVGIQFGPDVTEKFCKDNNL 442
            :|   |..|    .|..:|||:||....|          :....||:...|........||..|:
Worm   206 DR---PVAEILPDSLAQDLLWADPADGQGAMTVRSTPEYVPNGVRGLSFIFNEAAVRDTCKRLNI 267

  Fly   443 DYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVPHPDVK 507
            :.|:|:|::...|::...:.|.:|:||||.|.:...|.||.:.:..:. |.|...|.   |   |
Worm   268 NLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLRVETDG-KLNIGRFR---H---K 325

  Fly   508 PMAYANS 514
            .:.:|||
Worm   326 KLLHANS 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	99/329 (30%)
		PP2Ac	226..502	CDD:197547	93/304 (31%)
F49E11.7	NP_502500.3	PP2Ac	31..326	CDD:197547	94/309 (30%)
F49E11.7	NP_502500.3	MPP_PPP_family	61..311	CDD:277316	84/253 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900