DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and F20D6.6

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_505103.2	Gene:	F20D6.6 / 184725	WormBaseID:	WBGene00017636	Length:	316	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	76/337 - (22%)
Similarity:	144/337 - (42%)	Gaps:	62/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 EDGKVTLKFMKELMEHYKAQKRLHRKFAYKILCEIDTYMRAQPSLVD-------ITVPDEEKFTI 261
            ::|.....|.:|:::.:..:..:..::::..|.|:   :.....::|       ||.|    ..|
Worm     6 QNGGNERNFYEEIIQIHLQKGPVEHEYSFGFLSEL---LEDALEIMDGTSRVEYITPP----VNI 63

  Fly   262 CGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARG-- 324
            ||||..::.|:::||:..|.|.|:. |:|.|:.:|.|.||:|.:..|...|:.||.:|.:.||
Worm    64 CGDIRSRYGDVLDIFKTCGWPFEQK-YVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFY 127

  Fly   325 NHESINMNQMYGFTGEVTAKYT-----SAMADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVT 384
            .||.:..::  .|.||:..::.     .|:..|...:...||:...:|:|:|.::|       :.
Worm   128 EHELVKSDR--SFIGELRVRFPDSNKWQALNAIIKSLLKRLPVMTVLNRKLLCVNG-------MV 183

  Fly   385 LDHIRRIERNCQPPEEGLMCELLWSDPQQWMGLGQSKRGVGIQF------GP----------DVT 433
            ..:|:. |:|....:.|.|.|             .....|.:||      .|          .:.
Worm   184 TSNIKN-EKNVVSVKNGNMFE-------------NHNTRVEVQFLDIDIPSPVTPNKIDEESKII 234

  Fly   434 EKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSF 498
            ::..|..::..:|.|:.|...||......:.||:.|.........|.|..:.:..:| |.|:||.
Worm   235 KELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHN-KVNFKSI 298

  Fly   499 EAVPHPDVKPMA 510
            :.:...|...:|
Worm   299 QGIDGEDRTDLA 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	76/337 (23%)
		PP2Ac	226..502	CDD:197547	71/305 (23%)
F20D6.6	NP_505103.2	MPP_superfamily	39..285	CDD:387346	65/276 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900