DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and C25A6.1

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_504432.3	Gene:	C25A6.1 / 178923	WormBaseID:	WBGene00016081	Length:	300	Species:	Caenorhabditis elegans

Alignment Length:	271	Identity:	110/271 - (40%)
Similarity:	146/271 - (53%)	Gaps:	33/271 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 HRKFAYKILCE----------IDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGL 281
            |.|...:::.|          :|.:.| |.|:|::..|    ..:||||||||.||:.:|...|.
Worm    19 HEKLLSEVITEGRVLKLLDLALDVFKR-QKSMVEMNAP----IKVCGDIHGQFPDLLRLFHRGGW 78

  Fly   282 PSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYT 346
            |...| |||.||:||||.||:|.|..|..:|:.:|.:.||.|||||...:|::|||..|...:|.
Worm    79 PPTAN-YLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQ 142

  Fly   347 SA-MADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSD 410
            |. |...|..||||||||..|..|||.|||||..:.|               .:|.|:.:|||:|
Worm   143 SVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHD---------------GKERLVADLLWAD 192

  Fly   411 PQQWM-GLGQSKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYC 474
            |...: |..::.||.|..||.|...|.|.|..||.|.|:|:|...|||.....|.:|:||||:||
Worm   193 PISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYC 257

  Fly   475 DTMGNMGAFIT 485
            ....|..||::
Worm   258 GQFDNCAAFMS 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	110/271 (41%)
		PP2Ac	226..502	CDD:197547	110/271 (41%)
C25A6.1	NP_504432.3	MPP_superfamily	5..282	CDD:301300	110/271 (41%)
C25A6.1	NP_504432.3	PP2Ac	32..284	CDD:197547	107/258 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810