DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and ZC477.2

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_501111.2	Gene:	ZC477.2 / 177485	WormBaseID:	WBGene00022617	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	343	Identity:	94/343 - (27%)
Similarity:	157/343 - (45%)	Gaps:	60/343 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 KFMKELMEHYKAQKRLHRKFAYK---ILCE--IDTYMRAQPSLVDITVPDEEKFTICGDIHGQFY 270
            :|:|::::..:..||.....:..   .:|.  ||.:.:.| :|::::.|    .|:.||:||.|:
Worm    33 EFLKKMIQPGRVMKRSKNNLSSNEVWSVCRAVIDEFKKEQ-NLMEVSAP----VTVIGDVHGNFH 92

  Fly   271 DLMNI----------------FEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHF 319
            ||...                |.......:|  |:|.|:::|:|..|:|||..||.||:.:|..:
Worm    93 DLYRALLARTEQDITDEQKSNFSTRQFVRDK--YVFLGNYIDKGPRSIECICLLFAFKICFPQKY 155

  Fly   320 FLARGNHE--SINMNQMYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVMHGG----LF 378
            .|.||.||  |:|.::..|.....:..:...:...|.:.|:|:||...:.||||.:|||    |.
Worm   156 ILLRGPHECPSVNSSEFLGVMETFSPNHFKKIHKKFNEAFSWMPLAAVVGQKILCVHGGISPRLT 220

  Fly   379 STEDVTLDHIRRIERNCQ-PPEEGLMCELLWSDPQQW--MGLGQSK--------RGVGIQFGPDV 432
            |.||     ||:|:|..: ..|:.|..:||::|...:  :.:...|        |.:.:.:....
Worm   221 SWED-----IRKIKRPLKDATEDPLATDLLFADTLDFDLIHIPTRKPKYEFNVIRNMSVMYNEAA 280

  Fly   433 TEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGN------NL 491
            ..:||:..||..|||||.....||......:.||:|::..: ....|.||.:.|.||      :|
Worm   281 VTQFCEKFNLKLIIRSHMKVPFGYRFFSEKRLITIFNSTGF-QNESNYGAVLKIDGNAKITIISL 344

  Fly   492 KPNYKSFEA---VPHPDV 506
            .|.....|.   ..|.|:
Worm   345 LPQQSKAEVQEKAHHSDM 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	94/343 (27%)
		PP2Ac	226..502	CDD:197547	88/322 (27%)
ZC477.2	NP_501111.2	PP2Ac	52..348	CDD:197547	87/308 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900