DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and pph-4.1

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_499603.1	Gene:	pph-4.1 / 176657	WormBaseID:	WBGene00004085	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	285	Identity:	123/285 - (43%)
Similarity:	163/285 - (57%)	Gaps:	13/285 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 KILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDR 297
            |.||.....:.|:...|.:.   :...||||||||||||||.:|::.| |.....|||.||||||
Worm    51 KTLCAKAREILAEEGNVQVI---DSPVTICGDIHGQFYDLMELFKVGG-PVPNTNYLFLGDFVDR 111

  Fly   298 GSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSAMA-DIFTQVFNWLP 361
            |.:|||....|...|..||:...|.||||||..:.|:|||..|...||.:|.. ...|:||::|.
Worm   112 GFYSVETFLLLLALKARYPDRMMLIRGNHESRQITQVYGFYDECLRKYGNASVWKHCTEVFDYLS 176

  Fly   362 LCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQW-MGLGQSKRGVG 425
            |...|:.|:..:|||| |....|:|.||.|:|..:.|.:|.||:||||||::. :|.|.|.||.|
Worm   177 LAAVIDGKVFCVHGGL-SPSISTMDQIRVIDRKQEVPHDGPMCDLLWSDPEEGNVGWGLSPRGAG 240

  Fly   426 IQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNN 490
            ..||.|.::.||:.|.:|.|.|:|::...||:...|.|.:||:||||||...||:.|.:.: ..|
Worm   241 YLFGADASKTFCETNGVDLICRAHQLVMEGYKWHFNEKVLTVWSAPNYCYRCGNVAAILEL-DEN 304

  Fly   491 LKPNYKSFEAVPH-----PDVKPMA 510
            |...:..|||.|.     |..||.|
Worm   305 LNKEFTIFEAAPQENRGAPAKKPHA 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	123/285 (43%)
		PP2Ac	226..502	CDD:197547	118/270 (44%)
pph-4.1	NP_499603.1	PTZ00239	31..333	CDD:173488	123/285 (43%)
pph-4.1	NP_499603.1	MPP_PP2A_PP4_PP6	31..316	CDD:277360	118/270 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810