DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpD3 and F58G1.3

DIOPT Version :9

Sequence 1:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_496754.2	Gene:	F58G1.3 / 174933	WormBaseID:	WBGene00010265	Length:	364	Species:	Caenorhabditis elegans

Alignment Length:	371	Identity:	119/371 - (32%)
Similarity:	180/371 - (48%)	Gaps:	60/371 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 NDKDAKLKFTECNKIVKMRAFERAIAVDKPE---------KTLSEMYSDMENITIEDDYKGPQLE 204
            |.|.:|    |..|..::..|:  :|.:.|.         |.::.:|.| .||.|.:...|.::
Worm     8 NKKGSK----EGPKTSEISKFD--LAKENPRLAEWMDDCIKRMNSLYKD-TNINICNVMTGHEI- 64

  Fly   205 DGKVTLKFMKELMEHYKAQKRLHRKFAYKILCEIDTYMRAQPSLVDITVPDEEKFTICGDIHGQF 269
                                       ..|:..::.....:.:|.:...|    ..:.||||.||
Worm    65 ---------------------------IAIIRMVEAIFMDESNLCEAEAP----IKVIGDIHAQF 98

  Fly   270 YDLMNIFEING-LPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQ 333
            .|:..:|::.| :|.||  .:|.||:||||...:|.:..||..|:.|.:..:|.|||||:.::|:
Worm    99 QDMNRLFDLIGRVPEEK--LMFLGDYVDRGPQGIEVLILLFCLKIRYRDRIYLLRGNHETPSVNK 161

  Fly   334 MYGFTGEVTAKYTSAMADIFTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPP 398
            :|||..|...||...:...|...||.:|:...|::::|.||||| |.|.:.||.||.|.|.|:|.
Worm   162 IYGFYVECQYKYGVGLWWDFQTCFNRMPMSGLISKRVLCMHGGL-SPELINLDTIRNIPRPCEPL 225

  Fly   399 EEGLMCELLWSDP----QQWMGLGQSKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVA 459
            :.||:.:||||||    :.|.   .|.||:...||..|.|:.||...:|.|||.|:|...|||:.
Worm   226 DRGLLIDLLWSDPTNKGEGWF---HSIRGISYMFGKGVVEQACKSLEIDLIIRGHQVVQDGYEMM 287

  Fly   460 HNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVPHPD 505
            ...:.|||||.||||....|..|.:.:.. ||:.:::.....|.||
Worm   288 AGRRLITVFSVPNYCAQFTNAAAVVCLNA-NLQVSFQQLIPPPLPD 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	105/313 (34%)
		PP2Ac	226..502	CDD:197547	101/280 (36%)
F58G1.3	NP_496754.2	MPP_superfamily	37..327	CDD:301300	108/329 (33%)
F58G1.3	NP_496754.2	PP2Ac	59..329	CDD:197547	102/308 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900